Publication Name	World Journal of Hepatology
Manuscript ID	16188
Country	Italy

Received	2015-01-02 10:29
Peer-Review Started	2015-01-02 19:39
First Decision by Editorial Office Director
Return for Revision	2015-02-03 20:37
Revised	2015-02-05 06:16
Publication Fee Transferred
Second Decision by Editor	2015-04-30 16:01
Second Decision by Editor-in-Chief	2015-04-30 16:43
Final Decision by Editorial Office Director	2015-06-16 16:33
Articles in Press	2015-06-16 16:33
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-17 17:33
Publish the Manuscript Online	2015-08-08 13:55

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Editorial
Article Title	Selection tool alpha-fetoprotein for patients waiting for liver transplantation: How to easily manage a fractal algorithm
Manuscript Source	Invited Manuscript
All Author List	Quirino Lai, Giovanni Battista Levi Sandri and Jan Lerut
Funding Agency and Grant Number
Corresponding Author	Dr. Quirino Lai, MD, Transplant Unit, Department of Surgery, University Aquila, San Salvatore Hospital, Via Vetoio 1, 67010 Aquila, Italy. lai.quirino@libero.it
Key Words	Alpha-fetoprotein; Hepatocellular cancer; Milan criteria; Recurrence; Drop-out
Core Tip	Alpha-fetoprotein (AFP) behavior in patients with hepatocellular carcinoma waiting for liver trans-plant (LT) represents a perfect example of a fractal model. Consequently, AFP represents a useful but poorly mana-geable selection tool for patients waiting for LT. Looking at the recent literature, we can assume that: (1) last AFP value seem to be the best values to adopt; (2) different cut-offs may be adopted in the two different scenarios of Milan Criteria (MC) IN and MC OUT status; (3) AFP cut-off of 1000 ng/mL represent a good compromise for MC-IN patients; and (4) no definitive conclusion has been reached in relation to MC-OUT patients.
Publish Date	2015-08-08 13:55
Citation	Lai Q, Levi Sandri GB, Lerut J. Selection tool alpha-fetoprotein for patients waiting for liver transplantation: How to easily manage a fractal algorithm. World J Hepatol 2015; 7(15): 1899-1904
URL	http://www.wjgnet.com/1948-5182/full/v7/i15/1899.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i15.1899

Full Article (PDF)	WJH-7-1899.pdf
Full Article (Word)	WJH-7-1899.doc
Manuscript File	16188-Review.doc
Answering Reviewers	16188-Answering reviewers.pdf
Audio Core Tip	16188-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	16188-Conflict-of-interest statement.pdf
Copyright License Agreement	16188-Copyright assignment.pdf
Peer-review Report	16188-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16188-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16188-Scientific misconduct check.pdf
Scientific Editor Work List	16188-Scientific editor work list .pdf