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4/29/2015 7:04:00 PM | Browse: 626 | Download: 1706
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Received |
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2015-01-17 12:30 |
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Peer-Review Started |
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2015-01-18 16:07 |
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To Make the First Decision |
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2015-02-07 14:49 |
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Return for Revision |
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2015-02-25 16:22 |
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Revised |
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2015-03-02 16:52 |
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Second Decision |
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2015-03-16 18:11 |
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Accepted by Journal Editor-in-Chief |
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2015-03-17 07:48 |
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Accepted by Executive Editor-in-Chief |
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2015-04-07 16:06 |
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Articles in Press |
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2015-04-07 16:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-04-24 10:33 |
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Publish the Manuscript Online |
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2015-04-29 16:58 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Inflammatory bowel disease: Traditional knowledge holds the seeds for the future
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Giovanni C Actis, Rinaldo Pellicano and Floriano Rosina |
| Funding Agency and Grant Number |
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| Corresponding Author |
Giovanni C Actis, MD, Hepatogastroenterology Division, Ospedale Gradenigo, Corso Regina Margherita, 8, 10153 Torino, Italy. segreteria.gel@h-gradenigo.it |
| Key Words |
Inflammatory bowel disease; Microbiome; Stem cells; Future treatments; Curative appendectomy |
| Core Tip |
The inflammatory diseases of the gut (inflam?matory bowel disease) continue to both constitute a medical challenge, and a formidable intellectual stimulus. The latter statement is based on the accumulating evidence that the IBDS are indeed syndromes whereby a few poorly penetrating polymorphic genes can affect at once the inflammatory balance in the barrier systems of the gut, the skin, and the airways. The former statement reflects the very fact that, though described in the 19th century, IBD continues to defeat our struggle to cure it, invading yet the hitherto unaffected landscapes of the Eastern World, almost as it was a response to our efforts. We deem that the address of the initiating factors, rather than the downstream phenomena, may be a strategy to wriggle out of the hold-up. The description of interventions such as appendectomy or microbiome replacement, among other options, witnesses our own way to interpret this need in the present editorial. |
| Publish Date |
2015-04-29 16:58 |
| Citation |
Actis GC, Pellicano R, Rosina F. Inflammatory bowel disease: Traditional knowledge holds the seeds for the future. World J Gastrointest Phar¬macol Ther 2015; 6(2): 10-16 |
| URL |
http://www.wjgnet.com/2150-5349/full/v6/i2/10.htm |
| DOI |
http://dx.doi.org/10.4292/wjgpt.v6.i2.10 |
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