Publication Name	World Journal of Gastroenterology
Manuscript ID	16734
Country	Argentina

Received	2015-01-28 08:38
Peer-Review Started	2015-01-28 17:43
To Make the First Decision	2015-03-10 17:49
Return for Revision	2015-03-12 10:40
Revised	2015-03-21 01:23
Second Decision	2015-04-10 11:54
Accepted by Journal Editor-in-Chief	2015-04-10 17:23
Accepted by Executive Editor-in-Chief	2015-04-17 15:52
Articles in Press	2015-04-17 16:25
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-05-22 08:23
Typeset the Manuscript	2015-06-02 16:19
Publish the Manuscript Online	2015-06-20 17:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Biochemistry & Molecular Biology
Manuscript Type	Minireviews
Article Title	Molecular aspects of the intestinal calcium absorption
Manuscript Source	Invited Manuscript
All Author List	Gabriela Diaz de Barboza, Solange Guizzardi and Nori Tolosa de Talamoni
Funding Agency and Grant Number
Corresponding Author	Nori Tolosa de Talamoni, Professor, Cátedra de Bioquímica y Biología Molecular, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Av. Haya de la Torre s/n, Córdoba 5000, Argentina. ntolosa@biomed.fcm.unc.edu.ar
Key Words	Intestinal Ca2+ absorption; Transcellular pathway; Paracellular route; 1; 25(OH)2D3; PTH; Prolactin; Estrogen; Lactation; Pregnancy; Aging
Core Tip	The intestinal Ca2+ absorption occurs through transcellular and paracellular pathways. Apparently, novel proteins such as Cav1.3 and 4.1R protein are involved in the Ca2+ transcellular pathway. Proteins involved in the tight junction structures such as Claudins 2, 12 and 15 participate in the paracellular pathway. There is evidence of a crosstalk between the transcellular and the paracellular pathways. To know the molecular details of the intestinal Ca2+ absorption could lead to develop nutritional and medical strategies to optimize the efficiency of intestinal Ca2+ absorption and to prevent osteoporosis and other pathologies related to Ca2+ metabolism.
Publish Date	2015-06-20 17:38
Citation	Diaz de Barboza G, Guizzardi S, Tolosa de Talamoni N. Molecular aspects of intestinal calcium absorption. World J Gastroenterol 2015; 21(23): 7142-7154
URL	http://www.wjgnet.com/1007-9327/full/v21/i23/7142.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i23.7142

Full Article (PDF)	WJG-21-7142.pdf
Full Article (Word)	WJG-21-7142.doc
Manuscript File	16734-Review.doc
Answering Reviewers	16734-Answering reviewers.pdf
Audio Core Tip	16734-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	16734-Conflict-of-interest statement.pdf
Copyright License Agreement	16734-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	16734-Language certificate.pdf
Peer-review Report	16734-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16734-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16734-Scientific misconduct check.pdf
Scientific Editor Work List	16734-Scientific editor work list.pdf