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8/17/2015 4:52:00 PM | Browse: 615 | Download: 1651
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Received |
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2015-01-29 10:00 |
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Peer-Review Started |
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2015-02-01 19:43 |
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To Make the First Decision |
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2015-03-06 10:10 |
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Return for Revision |
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2015-03-15 18:32 |
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Revised |
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2015-03-21 04:39 |
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Second Decision |
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2015-06-09 17:38 |
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Accepted by Journal Editor-in-Chief |
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2015-06-10 04:18 |
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Accepted by Company Editor-in-Chief |
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2015-06-16 16:56 |
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Articles in Press |
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2015-06-16 16:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-07-28 18:52 |
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Publish the Manuscript Online |
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2015-08-17 11:09 |
ISSN |
2218-6239 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Allergy |
Manuscript Type |
Review |
Article Title |
Ocular renin-angiotensin system with special reference in the anterior part of the eye
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Manuscript Source |
Invited Manuscript |
All Author List |
Mervi Holappa, Heikki Vapaatalo and Anu Vaajanen |
Funding Agency and Grant Number |
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Corresponding Author |
Anu Vaajanen, MD, PhD, Department of Ophthalmology, Tampere University Hospital, P.O. Box 2000, 33521 Tampere, Finland. anu.vaajanen@fimnet.fi |
Key Words |
Angiotensin converting enzyme 1; Angiotensin converting enzyme 2; Angiotensin converting enzyme-inhibitors; Angiotensin Ⅱ; Angiotensin (1-9); Angiotensin (1-7); Glaucoma; Intraocular pressure; Renin-angiotensin system |
Core Tip |
Many of the central components of renin-angiotensin system (RAS) have been identified in different structures of the human eye. Recent findings suggest that local RAS accounts for long term changes in ocular tissue level. Antihypertensive drugs which inhibit RAS (Angiotensin converting enzyme or AT-receptor blockade) reduce intraocular pressure suggesting their possibility as anti-glaucomatous drugs in the future. Here we describe the local intraocular RAS especially in the anterior part of eye. |
Publish Date |
2015-08-17 11:09 |
Citation |
Holappa M, Vapaatalo H, Vaajanen A. Ocular renin-angiotensin system with special reference in the anterior part of the eye. World J Ophthalmol 2015; 5(3): 110-124 |
URL |
http://www.wjgnet.com/2218-6239/full/v5/i3/110.htm |
DOI |
http://dx.doi.org/10.5318/wjo.v5.i3.110 |
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