Publication Name	World Journal of Ophthalmology
Manuscript ID	16791
Country

Received	2015-01-29 08:22
Peer-Review Started	2015-01-29 17:32
First Decision by Editorial Office Director
Return for Revision	2015-03-11 18:34
Revised	2015-04-30 03:38
Publication Fee Transferred
Second Decision by Editor	2015-07-06 08:32
Second Decision by Editor-in-Chief	2015-07-09 17:44
Final Decision by Editorial Office Director	2015-07-17 14:26
Articles in Press	2015-07-17 14:26
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-07-29 08:51
Publish the Manuscript Online	2015-08-17 11:09

ISSN	2218-6239 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Ophthalmology
Manuscript Type	Editorial
Article Title	Pharmacologic vitreolysis: New strategy for treatment of anomalous vitreo-macular adhesion
Manuscript Source	Invited Manuscript
All Author List	Desislava N Koleva-Georgieva
Funding Agency and Grant Number
Corresponding Author	Desislava N Koleva-Georgieva, MD, PhD, FEBO, Assistant Professor, Department of Ophthalmology, Faculty of Medicine, Medical University of Plovdiv, Pestersko shose 66, 4001 Plovdiv, Bulgaria. dr_desikoleva@yahoo.com
Key Words	Pharmacologic vitreolysis; Vitreo-macular adhesion; Posterior vitreous detachment; Macular hole; Microplasmin
Core Tip	Persistent anomalous vitreo-macular adhesion (VMA) is a well-known factor, associated with a variety of sight threatening diseases (macular hole, vitreo-macular traction syndrome, macular edema, exudative age-related macular degeneration). The release of traction has been of exclusive surgical capability. Not with standing good results, vitrectomy is hampered by the inability of complete vitreo-retinal separation and surgical complications. With aim to overcome limitations of surgery, investigators have made enormous progress with the advent of pharmacologic vitreolysis - a method for releasing VMA by intravitreal drug delivery. This paper aims to summarize the current knowledge and status of investigation on this new treatment approach.
Publish Date	2015-08-17 11:09
Citation	Koleva-Georgieva DN. Pharmacologic vitreolysis: New strategy for treatment of anomalous vitreo-macular adhesion. World J Ophthalmol 2015; 5(3): 99-105
URL	http://www.wjgnet.com/2218-6239/full/v5/i3/99.htm
DOI	http://dx.doi.org/10.5318/wjo.v5.i3.99

Full Article (PDF)	WJO-5-99.pdf
Full Article (Word)	WJO-5-99.doc
Manuscript File	16791-Review.docx
Answering Reviewers	16791-Answering reviewers.pdf
Audio Core Tip	16791-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	16791-Conflict-of-interest statement.pdf
Copyright License Agreement	16791-Copyright assignment.pdf
Peer-review Report	16791-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	16791-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	16791-Scientific misconduct check.pdf
Scientific Editor Work List	16791-Scientific editor work list.pdf