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9/17/2015 11:57:00 AM | Browse: 630 | Download: 1601
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Received |
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2015-04-26 17:51 |
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Peer-Review Started |
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2015-04-27 18:45 |
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To Make the First Decision |
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2015-06-02 15:16 |
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Return for Revision |
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2015-06-09 12:46 |
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Revised |
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2015-06-23 14:38 |
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Second Decision |
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2015-07-17 17:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-07-18 11:41 |
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Articles in Press |
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2015-07-18 11:41 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-08-10 10:00 |
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Typeset the Manuscript |
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2015-08-27 17:05 |
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Publish the Manuscript Online |
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2015-09-14 16:54 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Circulating microRNAs as diagnostic and prognostic tools for hepatocellular carcinoma
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yu-Cheng Zhang, Zhuo Xu, Tian-Fu Zhang and Ya-Li Wang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Department of Public Health of Jilin Province of China |
2009Z080 |
| Department of Public Health of Jilin Province of China |
2014Q025 |
| Supporting Program of Bethune Medical Research of Jilin University |
2013207058 |
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| Corresponding Author |
Ya-Li Wang, MD, PHD, Department of Blood Transfusion, China-Japan Union Hospital, Jilin University, Changchun 130033, Jilin Province, China. zhang4083@163.com |
| Key Words |
Circulating microRNAs; Diagnosis; Prognosis; Hepatocellular carcinoma; Biomarkers |
| Core Tip |
MicroRNAs (miRNAs) play critical roles in cell growth, differentiation, and the development of hepatocellular carcinoma (HCC). The study of circulating miRNAs is a rapidly growing field of research, indicating the potential applications of miRNAs as minimally invasive biomarkers for HCC diagnosis, recurrence monitoring and prognosis. This review highlights current understanding of miRNA biogenesis and the origins and types of circulating miRNAs and summarizes recent progress in the study of circulating miRNAs as diagnostic and prognostic biomarkers for HCC. We also discuss the challenges and perspectives regarding the clinical utility of circulating miRNAs in HCC. |
| Publish Date |
2015-09-14 16:54 |
| Citation |
Zhang YC, Xu Z, Zhang TF, Wang YL. Circulating microRNAs as diagnostic and prognostic tools for hepatocellular carcinoma. World J Gastroenterol 2015; 21(34): 9853-9862 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i34/9853.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i34.9853 |
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