Publication Name	World Journal of Hepatology
Manuscript ID	19855
Country	United States

Received	2015-05-24 12:43
Peer-Review Started	2015-05-26 10:20
To Make the First Decision	2015-08-14 15:29
Return for Revision	2015-08-18 12:17
Revised	2015-09-01 23:40
Second Decision	2015-09-07 11:33
Accepted by Journal Editor-in-Chief	2015-09-08 17:02
Accepted by Executive Editor-in-Chief	2015-09-16 19:14
Articles in Press	2015-09-16 19:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-09-17 16:56
Publish the Manuscript Online	2015-10-02 19:06

ISSN	1948-5182 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Pathogenesis of hepatocarcinogenesis in non-cirrhotic nonalcoholic fatty liver disease: Potential mechanistic pathways
Manuscript Source	Invited Manuscript
All Author List	Ryan B Perumpail, Andy Liu, Robert J Wong, Aijaz Ahmed and Stephen A Harrison
Funding Agency and Grant Number
Corresponding Author	Aijaz Ahmed, MD, Associate Professor of Medicine, Medical Director of Liver Transplant Program, Division of Gastroenterology and Hepatology, Liver Transplant Program, Stanford University School of Medicine, 750 Welch Road, Suite 210, Stanford, CA 94305, United States. aijazahmed@stanford.edu
Key Words	Nonalcoholic steatohepatitis; Hepatocellular carcinoma; Metabolic syndrome; Nonalcoholic fatty liver disease
Core Tip	Although hepatocellular carcinoma (HCC) primarily arises in the background of liver cirrhosis, the development of HCC in nonalcoholic fatty liver disease (NAFLD) without cirrhosis is increasingly recognized. The pathogenesis of NAFLD associated non-cirrhotic HCC is distinct from that of cirrhotic HCC because the metabolic syndrome along with obesity and insulin resistance underlie several unique mechanisms that promote tumorigenesis.
Publish Date	2015-10-02 19:06
Citation	Perumpail RB, Liu A, Wong RJ, Ahmed A, Harrison SA. Pathogenesis of hepatocarcinogenesis in non-cirrhotic non­alcoholic fatty liver disease: Potential mechanistic pathways. World J Hepatol 2015; 7(22): 2384-2388
URL	http://www.wjgnet.com/1948-5182/full/v7/i22/2384.htm
DOI	http://dx.doi.org/10.4254/wjh.v7.i22.2384

Full Article (PDF)	WJH-7-2384.pdf
Full Article (Word)	WJH-7-2384.doc
Manuscript File	19855-Review.docx
Answering Reviewers	19855-Answering reviewers.pdf
Audio Core Tip	19855-Audio core tip.wma
Conflict-of-Interest Disclosure Form	19855-Conflict-of-interest statement.pdf
Copyright License Agreement	19855-Copyright assignment.pdf
Peer-review Report	19855-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	19855-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	19855-Scientific misconduct check.pdf
Scientific Editor Work List	19855-Scientific editor work list.pdf