Publication Name	World Journal of Cardiology
Manuscript ID	20354
Country	United States

Received	2015-06-02 08:54
Peer-Review Started	2015-06-06 20:36
To Make the First Decision	2015-08-16 16:58
Return for Revision	2015-08-22 15:39
Revised
Second Decision	2015-12-09 17:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-18 16:43
Articles in Press	2015-12-18 16:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-08 14:19
Publish the Manuscript Online	2016-03-22 10:41

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Exercise oscillatory ventilation: Mechanisms and prognostic significance
Manuscript Source	Invited Manuscript
All Author List	Bishnu P Dhakal and Gregory D Lewis
Funding Agency and Grant Number
Corresponding Author	Gregory D Lewis, MD, Heart Failure and Cardiac Transplantation Unit, Massachusetts General Hospital, Bigelow 800, 55 Fruit Street, Boston, MA 02114, United States. glewis@partners.org
Key Words	Exercise; Oscillatory ventilation; Heart failure
Core Tip	Alteration in breathing patterns in patients with advanced heart failure (HF) characterized by cyclic variation of ventilation with a period of approximately one minute is known as periodic breathing. Periodic breathing during exercise, known as exercise oscillatory ventilation (EOV), is an oscillatory ventilatory pattern during exercise that persists for at least 60% of the exercise test with an amplitude ≥ 15% of the average resting value. Circulatory delay, pulmonary congestion and chemoreceptor sensitivity has been proposed to cause generation of EOV. EOV is found to be an independent predictor of worse outcome irrespective of other gas exchange variables in HF patients.
Publish Date	2016-03-22 10:41
Citation	Dhakal BP, Lewis GD. Exercise oscillatory ventilation: Mechanisms and prognostic significance. World J Cardiol 2016; 8(3): 258-266
URL	http://www.wjgnet.com/1949-8462/full/v8/i3/258.htm
DOI	http://dx.doi.org/10.4330/wjc.v8.i3.258

Full Article (PDF)	WJC-8-258.pdf
Full Article (Word)	WJC-8-258.doc
Manuscript File	20354-Review.docx
Answering Reviewers	20354-Answering reviewers.pdf
Audio Core Tip	20354-Audio core tip.wma
Conflict-of-Interest Disclosure Form	20354-Conflict-of-interest statement.pdf
Copyright License Agreement	20354-Copyright assignment.pdf
Peer-review Report	20354-Peer-review(s).pdf
Scientific Misconduct Check	20354-Scientific misconduct check.pdf
Scientific Editor Work List	20354-Scientific editor work list.pdf