Publication Name	World Journal of Gastroenterology
Manuscript ID	20752
Country	China

Received	2015-06-20 14:09
Peer-Review Started	2015-06-21 21:33
First Decision by Editorial Office Director
Return for Revision	2015-07-14 19:21
Revised	2015-07-26 15:44
Publication Fee Transferred
Second Decision by Editor	2015-10-14 09:03
Second Decision by Editor-in-Chief	2015-10-14 22:47
Final Decision by Editorial Office Director	2015-10-26 17:59
Articles in Press	2015-10-26 17:59
Edit the Manuscript by Language Editor	2015-12-09 19:24
Typeset the Manuscript	2016-01-13 15:02
Publish the Manuscript Online	2016-01-23 17:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Basic Study
Article Title	Interleukin-22 contributes to liver regeneration in mice with concanavalin A-induced hepatitis after hepatectomy
Manuscript Source	Unsolicited Manuscript
All Author List	Ya-Min Zhang, Zi-Rong Liu, Zi-Lin Cui, Chao Yang, Long Yang, Yang Li and Zhong-Yang Shen
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81370576 Application Foundation and Advanced Technology Research Plan of Tianjin of China 14JCYBJC24800
Corresponding Author	Zi-Rong Liu, Postgraduate, First Central Clinic of Tianjin Medical University, No. 24 Fukang road, Nankai District, Tianjin 300192, China. liuzirong0730@163.com
Key Words	Interleukin-22; Concanavalin A; Partial hepatectomy; Liver regeneration
Core Tip	Interleukin (IL)-22 appears to play a protective role in inflammation and has also been demonstrated to have proliferative effects in a hepatocyte cell line, however, it has rarely been reported that the protective and proliferative effects exist simultaneously. In this article, we investigated the therapeutic effects and mechanisms of IL-22 in liver regeneration in mice with concanavalin A-induced liver injury following 70% hepatectomy. IL-22 played protective and survival roles against liver injury in this model.
Publish Date	2016-01-23 17:08
Citation	Zhang YM, Liu ZR, Cui ZL, Yang C, Yang L, Li Y, Shen ZY. Interleukin-22 contributes to liver regeneration in mice with concanavalin A-induced hepatitis after hepatectomy. World J Gastroenterol 2016; 22(6): 2081-2091
URL	http://www.wjgnet.com/1007-9327/full/v22/i6/2081.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i6.2081

Full Article (PDF)	WJG-22-2081.pdf
Full Article (Word)	WJG-22-2081.doc
Manuscript File	20752-Review.docx
Answering Reviewers	20752-Answering reviewers.pdf
Conflict-of-Interest Disclosure Form	20752-Conflict-of-interest statement.pdf
Copyright License Agreement	20752-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	20752-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate	20752-Language certificate.pdf
Peer-review Report	20752-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20752-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20752-Scientific misconduct check.pdf
Scientific Editor Work List	20752-Scientific editor work list.pdf