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4/11/2016 2:30:00 PM | Browse: 565 | Download: 1211
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Received |
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2015-10-25 11:22 |
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Peer-Review Started |
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2015-10-25 11:39 |
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To Make the First Decision |
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2015-11-27 17:30 |
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Return for Revision |
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2015-11-30 10:13 |
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Revised |
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2015-12-06 20:40 |
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Second Decision |
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2015-12-18 15:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-12-30 17:38 |
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Articles in Press |
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2015-12-30 17:38 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2016-02-16 15:08 |
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Typeset the Manuscript |
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2016-03-24 18:43 |
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Publish the Manuscript Online |
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2016-04-03 18:51 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kB signaling in colorectal cancer cells
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong Shen, Jun-Li Ma, Yan Zhang, Gan-Lu Deng, Yan-Ling Qu, Xiao-Ling Wu, Jing-Xuan He, Sai Zhang and Shan Zeng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
30770971 |
| National Natural Science Foundation of China |
81172470 |
| National Natural Science Foundation of China |
81070362 |
| National Natural Science Foundation of China |
81372629 |
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| Corresponding Author |
Shan Zeng, MD, PhD, Department of Oncology, Xiangya Hospital, Central South University, 87 Xiangyan Road, Changsha 410008, Hunan Province, China. zengshan2000@yeah.net |
| Key Words |
Colorectal cancer; Integrin-linked kinase; Epithelial-mesenchymal transition; Nuclear factor-κB; Overexpression |
| Core Tip |
In this study, the colorectal cancer cell line SW480 was stably transfected with integrin-linked kinase (ILK) plasmids, and the proliferation, metastasis, and invasion ability of the cells were tested. The results demonstrated that ILK overexpression improved the proliferation, metastasis, and invasion ability of cell line SW4802 and promoted the occurrence of the epithelial-mesenchymal transition in colorectal cancer cells. These effects may be mediated by the nuclear factor-κB signaling pathway. |
| Publish Date |
2016-04-03 18:51 |
| Citation |
Shen H, Ma JL, Zhang Y, Deng GL, Qu YL, Wu XL, He JX, Zhang S, Zeng S. integrin-linked kinase overexpression promotes epithelial-mesenchymal transition via nuclear factor-kB signaling in colorectal cancer cells. World J Gastroenterol 2016; 22(15): 3969-3977 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i15/3969.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i15.3969 |
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