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9/19/2016 4:17:00 PM | Browse: 692 | Download: 1380
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Received |
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2016-03-27 09:25 |
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Peer-Review Started |
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2016-03-27 18:13 |
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To Make the First Decision |
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2016-05-13 16:31 |
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Return for Revision |
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2016-05-14 20:22 |
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Revised |
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2016-05-17 07:51 |
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Second Decision |
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2016-06-29 10:54 |
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Accepted by Journal Editor-in-Chief |
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2016-06-29 21:54 |
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Accepted by Executive Editor-in-Chief |
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2016-07-13 11:53 |
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Articles in Press |
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2016-07-13 11:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-08-29 17:14 |
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Publish the Manuscript Online |
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2016-09-12 10:43 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Retrospective Cohort Study |
Article Title |
Association between serum vitamin D levels and gastric cancer: A retrospective chart analysis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Neil Vyas, Rafael Ching Companioni, Melik Tiba, Hassan Alkhawam, Carmine Catalano, Robert Sogomonian, Joel Baum and Aaron Walfish |
Funding Agency and Grant Number |
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Corresponding Author |
Neil Vyas, MD, Department of Internal Medicine, Elmhurst Hospital Center, 79-01 Broadway, Elmhurst, NY 11373, United States. neil.vyas@mssm.edu |
Key Words |
Gastric cancer; Adenocarcinoma; Vitamin D |
Core Tip |
In recent years, vitamin D deficiency (VDd) has been associated with several gastrointestinal malignancies largely mediated by vitamin D receptors. It affects multiple cellular processes such as inhibiting differentiation, metastasis, proliferation and inducing apoptosis and cell cycle arrest. All these mechanisms support vitamin D’s anti-cancer role. VDd removes the tumorigenic activity that it elicits from regulating cell cycle, inhibiting cellular proliferation, angiogenesis and molecular signaling. Several studies have revealed that vitamin D3 substantially promotes apoptosis in undifferentiated gastric malignant cells, specifically HCG-27. A retrospective research was conducted to find an association between vitamin D serum levels and gastric cancer. |
Publish Date |
2016-09-12 10:43 |
Citation |
Vyas N, Companioni RC, Tiba M, Alkhawam H, Catalano C, Sogomonian R, Baum J, Walfish A. Association between serum vitamin D levels and gastric cancer: A retrospective chart analysis. World J Gastrointest Oncol 2016; 8(9): 688-694 |
URL |
http://www.wjgnet.com/1948-5204/full/v8/i9/688.htm |
DOI |
http://dx.doi.org/10.4251/wjgo.v8.i9.688 |
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