Publication Name	World Journal of Gastroenterology
Manuscript ID	25935
Country	India

Received	2016-03-26 15:36
Peer-Review Started	2016-03-26 22:20
First Decision by Editorial Office Director
Return for Revision	2016-05-13 08:51
Revised	2016-06-10 20:00
Publication Fee Transferred
Second Decision by Editor	2016-06-28 09:07
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2016-07-06 18:27
Articles in Press	2016-07-06 18:28
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-08-01 16:25
Publish the Manuscript Online	2016-08-15 10:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hepatitis E: Discovery, global impact, control and cure
Manuscript Source	Invited Manuscript
All Author List	Mohammad S Khuroo, Mehnaaz S Khuroo and Naira S Khuroo
Funding Agency and Grant Number
Corresponding Author	Mohammad S Khuroo, Director, Digestive Diseases Centre, Dr. Khuroo’s medical Clinic, Sector 1, SK Colony, Qamarwari, Srinagar, Kashmir 190010, India. khuroo@yahoo.com
Key Words	Communicable diseases; Discovery; Hepatitis E; Hepatitis E virus; Vaccine; Zoonosis
Core Tip	Discovery of hepatitis E came to lime light when 1978-Kashmir epidemic of hepatitis was investigated. Hepatitis E is being recognized as a clinical entity of reemerging importance. Hepatitis E virus has marked heterogeneity and infects many animals like bats, camel, chicken, deer, boar, mongoose, pigs, rats, rabbit and cutthroat trout. Originally reported as a major health problem in poor-resource countries, hepatitis E is now recognized as an important clinical problem in the developed world. Zoonotic foodborne transmission of hepatitis E virus infections has relevance in solid organ transplant population. Major advances have been made in managing chronic hepatitis E. Hepatitis E causes a number of extrahepatic diseases, including a wide spectrum of neurological syndromes. Hepatitis E vaccine -239, marketed in China, has shown high efficacy with sustained protection for over four years.
Publish Date	2016-08-15 10:30
Citation	Khuroo MS, Khuroo MS, Khuroo NS. Hepatitis E: Discovery, global impact, control and cure. World J Gastroenterol 2016; 22(31): 7030-7045
URL	http://www.wjgnet.com/1007-9327/full/v22/i31/7030.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i31.7030

Full Article (PDF)	WJG-22-7030.pdf
Full Article (Word)	WJG-22-7030.doc
Manuscript File	25935-Review.docx
Answering Reviewers	25935-Answering reviewers.pdf
Audio Core Tip	25935-Audio core tip.wav
Conflict-of-Interest Disclosure Form	25935-Conflict-of-interest statement.pdf
Copyright License Agreement	25935-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	25935-Language certificate.pdf
Peer-review Report	25935-Peer-review(s).pdf
Scientific Misconduct Check	25935-Scientific misconduct check.pdf
Scientific Editor Work List	25935-Scientific editor work list.pdf