BPG is committed to discovery and dissemination of knowledge
Featured Articles
11/14/2016 2:34:00 PM | Browse: 547 | Download: 720
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 26102
Country/Territory Japan
Received
2016-03-29 09:26
Peer-Review Started
2016-04-01 13:07
To Make the First Decision
2016-05-23 10:01
Return for Revision
2016-05-25 19:17
Revised
2016-07-19 21:45
Second Decision
2016-09-05 09:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-09-18 14:19
Articles in Press
2016-09-18 14:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-11-07 20:29
Publish the Manuscript Online
2016-11-14 09:26
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Clinical impact of chemotherapy to improve tumor microenvironment of pancreatic cancer
Manuscript Source Invited Manuscript
All Author List Takahiro Tsuchikawa, Shintaro Takeuchi, Toru Nakamura, Toshiaki Shichinohe and Satoshi Hirano
Funding Agency and Grant Number
Corresponding Author Dr. Takahiro Tsuchikawa, Associate Professor, Department of Gastroenterological Surgery II, Hokkaido University Graduate School of Medicine, N-15 W-7, Sapporo 060-8638, Japan. tsuchi-t@med.hokudai.ac.jp
Key Words Pancreas cancer; Microenvironment; Chemo­therapy; Immune cells; Immunomodulation
Core Tip It has been gradually clear that the chemo-therapeutic agents are two-edged sword to have both immune promoting and suppressing effects. The cellular components of the tumor microenvironment including infiltrating T lymphocytes, dendritic cells, regulatory T cells, tumor associated macrophages, myeloid derived suppressor cells and cancer associated fibroblasts could be improved. Based on the better understanding of tumor microenvironment following chemotherapy, the treatment protocol could be modified as personalized medicine and the prognosis of pancreas cancer would be more improved utilizing multimodal treatment strategy.
Publish Date 2016-11-14 09:26
Citation Tsuchikawa T, Takeuchi S, Nakamura T, Shichinohe T, Hirano S. Clinical impact of chemotherapy to improve tumor micro­environment of pancreatic cancer. World J Gastrointest Oncol 2016; 8(11): 786-792
URL http://www.wjgnet.com/1948-5204/full/v8/i11/786.htm
DOI http://dx.doi.org/10.4251/wjgo.v8.i11.786
Full Article (PDF) WJGO-8-786.pdf
Full Article (Word) WJGO-8-786.doc
Manuscript File 26102-Review.docx
Answering Reviewers 26102-Answering reviewers.pdf
Audio Core Tip 26102-Audio core tip.wav
Conflict-of-Interest Disclosure Form 26102-Conflict-of-interest statement.pdf
Copyright License Agreement 26102-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 26102-Language certificate.pdf
Peer-review Report 26102-Peer-review(s).pdf
Scientific Misconduct Check 26102-Scientific misconduct check.pdf
Scientific Editor Work List 26102-Scientific editor work list.pdf