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9/5/2016 10:42:00 AM | Browse: 370 | Download: 589
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Received |
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2016-04-08 15:10 |
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Peer-Review Started |
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2016-04-09 13:38 |
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To Make the First Decision |
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2016-05-12 10:27 |
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Return for Revision |
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2016-05-12 10:57 |
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Revised |
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2016-06-07 09:38 |
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Second Decision |
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2016-06-20 08:18 |
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Accepted by Journal Editor-in-Chief |
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2016-06-22 20:21 |
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Accepted by Executive Editor-in-Chief |
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2016-07-21 15:59 |
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Articles in Press |
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2016-07-21 15:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-08-18 10:28 |
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Publish the Manuscript Online |
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2016-08-24 10:09 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Topic Highlights |
| Article Title |
Supportive therapies for prevention of hepatocellular carcinoma recurrence and preservation of liver function
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Taro Takami, Takahiro Yamasaki, Issei Saeki, Toshihiko Matsumoto, Yutaka Suehiro and Isao Sakaida |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Japan Society for the Promotion of Science |
26461009 |
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| Corresponding Author |
Takahiro Yamasaki, MD, PhD, Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami Kogushi, Ube, Yamaguchi 755-8505, Japan. t.yama@yamaguchi-u.ac.jp |
| Key Words |
Hepatocellular carcinoma; Liver cirrhosis; Branched-chain amino acids; Late evening snack; Iron chelators; Bone marrow cells |
| Core Tip |
Hepatocellular carcinoma (HCC) is one of the deadliest cancers in the world and is associated with a high risk of recurrence. Because liver function worsens upon repeated treatment for HCC recurrence, therapies that preserve liver function are essential. Here, we survey a variety of different therapeutic agents and then review the current status and prospects for prevention of HCC recurrence, particularly from the perspective of supportive therapy to preserve liver function. The agents included branched-chain amino acids (BCAA) supplementation, late evening snacking with BCAA, antiviral drugs, sorafenib, peretinoin, iron chelators, and bone marrow cells. |
| Publish Date |
2016-08-24 10:09 |
| Citation |
Takami T, Yamasaki T, Saeki I, Matsumoto T, Suehiro Y, Sakaida I. Supportive therapies for prevention of hepatocellular carcinoma recurrence and preservation of liver function. World J Gastroenterol 2016; 22(32): 7252-7263 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i32/7252.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i32.7252 |
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