Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	26677
Country	Italy

Received	2016-04-21 15:42
Peer-Review Started	2016-04-22 16:33
To Make the First Decision	2016-06-06 17:24
Return for Revision	2016-06-07 19:01
Revised	2016-06-27 00:52
Second Decision	2016-07-11 12:00
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-07-22 11:13
Articles in Press	2016-07-22 11:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-07-27 16:37
Publish the Manuscript Online	2016-08-10 15:41

ISSN	2150-5330 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Novel biomarkers of fibrosis in Crohn’s disease
Manuscript Source	Invited Manuscript
All Author List	Gianluca Pellino, Pierlorenzo Pallante and Francesco Selvaggi
Funding Agency and Grant Number	Funding Agency Grant Number NONE NONE
Corresponding Author	Francesco Selvaggi, MD, EBSQ (Colo.), Associate Professor of General Surgery, Unit of Colorectal Surgery, Department of Medical, Surgical, Neurological, Metabolic and Ageing Sciences, Second University of Naples, Piazza Miraglia 2, 80138 Naples, Italy. fselvaggi@hotmail.com
Key Words	Crohn’s disease; Fibrosis; Inflammatory bowel diseases; Diagnosis; Biomarkers
Core Tip	Fibrosis occurs in a disturbingly large proportion of patients suffering from Crohn’s disease (CD), and invasive procedures may be required for both its diagnosis and treatment. Several biomarkers of intestinal fibrosis have recently been proposed. Most of them still need to be validated, but they could be useful for obtaining an early diagnosis of fibrosis, thereby allowing timely treatment and delaying or even avoiding surgery. A comprehensive overview of recently introduced biomarkers of fibrosis in CD is presented, along with a discussion of the controversial areas remaining in this field.
Publish Date	2016-08-10 15:41
Citation	Pellino G, Pallante P, Selvaggi F. Novel biomarkers of fibrosis in Crohn’s disease. World J Gastrointest Pathophysiol 2016; 7(3): 266-275
URL	http://www.wjgnet.com/2150-5330/full/v7/i3/266.htm
DOI	http://dx.doi.org/10.4291/wjgp.v7.i3.266

Full Article (PDF)	WJGP-7-266.pdf
Full Article (Word)	WJGP-7-266.doc
Manuscript File	26677-Review.docx
Answering Reviewers	26677-Answering reviewers.pdf
Audio Core Tip	26677-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	26677-Conflict-of-interest statement.pdf
Copyright License Agreement	26677-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20160421114829.docx
Institutional Review Board Approval Form or Document	Institutional_Review_Board_Statement_20160421114817.docx
Non-Native Speakers of English Editing Certificate	26677-Language certificate.pdf
Peer-review Report	26677-Peer-review(s).pdf
Scientific Misconduct Check	26677-Scientific misconduct check.pdf
Scientific Editor Work List	26677-Scientific editor work list.pdf