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8/12/2016 5:51:00 PM | Browse: 487 | Download: 1102
Publication Name World Journal of Gastrointestinal Pathophysiology
Manuscript ID 26791
Country/Territory United States
Received
2016-04-26 17:41
Peer-Review Started
2016-04-28 08:44
To Make the First Decision
2016-06-12 09:17
Return for Revision
2016-06-16 11:16
Revised
2016-07-01 05:13
Second Decision
2016-07-14 14:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-07-22 11:22
Articles in Press
2016-07-22 11:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-07-27 16:37
Publish the Manuscript Online
2016-08-10 15:41
ISSN 2150-5330 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Review
Article Title Immunobiology of hepatocarcinogenesis: Ways to go or almost there?
Manuscript Source Invited Manuscript
All Author List Pavan Patel, Steven E Schutzer and Nikolaos Pyrsopoulos
Funding Agency and Grant Number
Corresponding Author Nikolaos Pyrsopoulos, Chief, Division of Gastroenterology and Hepatology, Rutgers-New Jersey Medical School, 185 South Orange Avenue, MSB H538, Newark, NJ 07101-1709, United States. pyrsopni@njms.rutgers.edu
Key Words Hepatocarcinogenesis; Adoptive cell therapy; Tumorigenesis; Hepatocellular carcinoma; Immunology; Tumorigenesis; Immunotherapy; Immunobiology; Immune checkpoint inhibitors
Core Tip Hepatocellular carcinoma is on the rise and is associated with high mortality. Cancer immunology is an expanding field with promise. This review will summarize the current concepts in the immunobiology of hepatocarcinogenesis including the interplay of a variety of immune cells involved in anti-tumor and pro-tumor effects. Oncogenic pathways currently known to effect hepatocarcinogenesis will also be discussed. Finally, currently tested and developed treatment modalities employing immunotherapy will be discussed with an outlook on future therapies.
Publish Date 2016-08-10 15:41
Citation Patel P, Schutzer SE, Pyrsopoulos N. Immunobiology of hepato¬carcinogenesis: Ways to go or almost there? World J Gastrointest Pathophysiol 2016; 7(3): 242-255
URL http://www.wjgnet.com/2150-5330/full/v7/i3/242.htm
DOI http://dx.doi.org/10.4291/wjgp.v7.i3.242
Full Article (PDF) WJGP-7-242.pdf
Full Article (Word) WJGP-7-242.doc
Manuscript File 26791-Review.doc
Answering Reviewers 26791-Answering reviewers.pdf
Audio Core Tip 26791-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 26791-Conflict-of-interest statement.pdf
Copyright License Agreement 26791-Copyright assignment.pdf
Peer-review Report 26791-Peer-review(s).pdf
Scientific Misconduct Check 26791-Scientific misconduct check.pdf
Scientific Editor Work List 26791-Scientific editor work list.pdf