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12/9/2016 2:10:00 PM | Browse: 715 | Download: 1831
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Received |
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2016-06-29 11:39 |
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Peer-Review Started |
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2016-07-01 13:46 |
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To Make the First Decision |
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2016-09-05 09:06 |
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Return for Revision |
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2016-09-05 15:50 |
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Revised |
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2016-09-16 05:44 |
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Second Decision |
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2016-09-28 11:25 |
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Accepted by Journal Editor-in-Chief |
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2016-09-29 11:11 |
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Accepted by Executive Editor-in-Chief |
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2016-10-18 16:32 |
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Articles in Press |
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2016-10-18 16:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-11-30 17:13 |
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Publish the Manuscript Online |
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2016-12-09 09:12 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemical Research Methods |
| Manuscript Type |
Basic Study |
| Article Title |
Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Stanley Irobekhian Reuben Okoduwa, Ismaila A Umar, Dorcas B James, Hajara M Inuwa and James D Habila |
| Funding Agency and Grant Number |
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| Corresponding Author |
Stanley Irobekhian Reuben Okoduwa, Researcher, Directorate of Research and Development, Nigerian Institute of Leather and Science Technology, P.M.B. 1034, Zaria 810004, Nigeria. siroplc@gmail.com |
| Key Words |
Extraction techniques; Microwave-assisted-extraction; Maceration; Phytoconstituents; Medicinal plants; Soxhlet; Anti-diabetes |
| Core Tip |
Extraction of active phytoconstituents from medicinal plants rely mostly on the use of appropriate extraction method. Different extraction techniques affect the yield and biological activity of phytocomponents. In this study, we observed that microwave assisted extraction produces significantly higher overall extract yield as well as in phenolic, saponin and tannin content. Cold maceration and soxhlet extraction produced higher flavonoid and alkaloid yield respectively. Maceration extracts exhibited significantly better hypoglycemic activities in diabetic rats compared to extracts from soxhlet and microwave assisted extraction. This study reveals that the choice of extraction protocol should depend primarily on the purpose of interest. |
| Publish Date |
2016-12-09 09:12 |
| Citation |
Okoduwa SIR, Umar IA, James DB, Inuwa HM, Habila JD. Evaluation of extraction protocols for anti-diabetic phytochemical substances from medicinal plants. World J Diabetes 2016; 7(20): 605-614 |
| URL |
http://www.wjgnet.com/1948-9358/full/v7/i20/605.htm |
| DOI |
http://dx.doi.org/10.4239/wjd.v7.i20.605 |
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