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11/29/2016 5:46:00 PM | Browse: 844 | Download: 2133
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Received |
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2016-06-29 14:07 |
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Peer-Review Started |
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2016-07-01 14:28 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2016-08-05 10:48 |
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Revised |
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2016-08-20 05:30 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2016-08-30 12:04 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2016-09-08 16:56 |
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Articles in Press |
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2016-09-08 16:56 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-11-18 13:06 |
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Publish the Manuscript Online |
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2016-11-24 18:18 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Dermatology |
| Manuscript Type |
Observational Study |
| Article Title |
Increased levels of circulating platelet-derived microparticles in psoriasis: Possible implications for the associated cardiovascular risk
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Evangelia Papadavid, Konstantina Diamanti, Aris Spathis, Maria Varoudi, Ioanna Andreadou, Kostas Gravanis, Kostas Theodoropoulos, Petros Karakitsos, John Lekakis, Dimitrios Rigopoulos and Ignatios Ikonomidis |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Ignatios Ikonomidis, MD, FESC, 2nd Department of Cardiology, University of Athens Medical School, Attikon Hospital, Rimini 1, Haidari, 12462 Athens,
Greece. ignoik@otenet.gr
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| Key Words |
Psoriasis; Atherosclerosis; Inflammation; Platelet activation; Platelet-derived microparticles |
| Core Tip |
Psoriasis is associated with increased risk of cardiovascular disease. The pathogenic mechanisms shared by the two diseases seem to converge onto “inflammation” phenomenon. Platelets have a potent role in inflammation. Herein we evaluated platelet activation in psoriasis patients compared to healthy controls, and investigated a potential association between platelet activation markers and the inflammatory burden of psoriasis, the latter assessed by serum levels of pivotal pro-inflammatory cytokines implicated in psoriasis. We conclude that the association between psoriasis and atherosclerosis may be related to excessive platelet-derived microparticles (PMPs) formation. The size class of PMPs was taken into consideration in our study.
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| Publish Date |
2016-11-24 18:18 |
| Citation |
Papadavid E, Diamanti K, Spathis A, Varoudi M, Andreadou I, Gravanis K, Theodoropoulos K, Karakitsos P, Lekakis J, Rigopoulos D, Ikonomidis I. Increased levels of circulating platelet-derived microparticles in psoriasis: Possible implications for the associated cardiovascular risk. World J Cardiol 2016; 8(11): 667-675 |
| URL |
http://www.wjgnet.com/1949-8462/full/v8/i11/667.htm |
| DOI |
http://dx.doi.org/10.4330/wjc.v8.i11.667 |
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