Publication Name	World Journal of Cardiology
Manuscript ID	28941
Country	Japan

Received	2016-07-22 09:44
Peer-Review Started	2016-07-26 09:16
To Make the First Decision	2016-09-05 09:18
Return for Revision	2016-09-06 08:26
Revised	2016-09-07 23:32
Second Decision	2016-09-20 15:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-10-09 10:42
Articles in Press	2016-10-09 10:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-12-09 13:50
Publish the Manuscript Online	2016-12-20 10:04

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Editorial
Article Title	Interaction of hyperlipidemia and reactive oxygen species: Insights from the lipid-raft platform
Manuscript Source	Invited Manuscript
All Author List	Eisuke Amiya
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Education, Culture, Sports, Science and Technology of Japan (to Amiya E) 26461103
Corresponding Author	Eisuke Amiya, MD, PhD, Department of Cardiovascular Medicine, Graduate School of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. amiyae-tky@umin.ac.jp
Key Words	Lipid raft; Hyperlipidemia; Free cholesterol; Reactive oxygen species; NADPH oxidase
Core Tip	Lipid raft is a membrane microdomain in which specific combinations of lipid components such as free cholesterol and proteins function to mediate and amplify a variety of cellular signals. The platform has a significant impact on the cellular reactions such as the production of reactive oxygen species, however, there are limited articles on the clinical relevance of this platform. Lipid disorder, such as hyperlipidemia, is one that significantly affects the platform, with the modification of associating cell functions in various ways. We focused on the effect derived from this platform in hyperlipidemia in this manuscript.
Publish Date	2016-12-20 10:04
Citation	Amiya E. Interaction of hyperlipidemia and reactive oxygen species: Insights from the lipid-raft platform. World J Cardiol 2016; 8(12): 689-694
URL	http://www.wjgnet.com/1949-8462/full/v8/i12/689.htm
DOI	http://dx.doi.org/10.4330/wjc.v8.i12.689

Full Article (PDF)	WJC-8-689.pdf
Full Article (Word)	WJC-8-689.doc
Manuscript File	28941-Review.docx
Answering Reviewers	28941-Answering reviewers.pdf
Audio Core Tip	28941-Audio core tip.wma
Conflict-of-Interest Disclosure Form	28941-Conflict-of-interest statement.pdf
Copyright License Agreement	28941-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	28941-Grant application form(s).pdf
Peer-review Report	28941-Peer-review(s).pdf
Scientific Misconduct Check	28941-Scientific misconduct check.pdf
Scientific Editor Work List	28941-Scientific editor work list.pdf