Publication Name	World Journal of Gastroenterology
Manuscript ID	29990
Country	United Kingdom

Received	2016-09-02 13:01
Peer-Review Started	2016-09-03 20:26
To Make the First Decision	2016-09-28 09:02
Return for Revision	2016-09-29 14:53
Revised	2016-10-10 00:27
Second Decision	2016-11-11 14:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-11-16 16:34
Articles in Press	2016-11-16 16:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-11-23 09:14
Publish the Manuscript Online	2016-12-06 17:24

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Hepatic steatosis and fibrosis: Non-invasive assessment
Manuscript Source	Invited Manuscript
All Author List	Rustam N Karanjia, Mary ME Crossey, I Jane Cox, Haddy KS Fye, Ramou Njie, Robert D Goldin and Simon D Taylor-Robinson
Funding Agency and Grant Number
Corresponding Author	Rustam N Karanjia, Liver Unit, Division of Digestive Health, Department of Surgery and Cancer, Imperial College London, St Mary's Campus, 10th Floor QEQM Wing, South Wharf Street, London W2 1NY, United Kingdom. rk2311@ic.ac.uk
Key Words	Hepatic steatosis; Fibrosis; Non-invasive assessment; Blood biomarker; Ultrasound
Core Tip	Ongoing hepatic fibrosis and steatosis are well recognised features of chronic liver disease. Liver biopsy is currently the gold standard for assessing the disease although this has an associated but low morbidity and mortality risk. Therefore, alternative methods of non-invasive assessment of liver disease are of relevance and importance. We outline the mechanisms of hepatic fibrosis and steatosis and review uses of non-invasive imaging and blood biomarkers as an alternative to liver biopsy.
Publish Date	2016-12-06 17:24
Citation	Karanjia RN, Crossey MME, Cox IJ, Fye HKS, Njie R, Goldin RD, Taylor-Robinson SD. Hepatic steatosis and fibrosis: Non-invasive assessment. World J Gastroenterol 2016; 22(45): 9880-9897
URL	http://www.wjgnet.com/1007-9327/full/v22/i45/9880.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i45.9880

Full Article (PDF)	WJG-22-9880.pdf
Full Article (Word)	WJG-22-9880.doc
Manuscript File	29990-Review.docx
Answering Reviewers	29990-Answering reviewers.pdf
Audio Core Tip	29990-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	29990-Conflict-of-interest statement.pdf
Copyright License Agreement	29990-Copyright assignment.pdf
Supplementary Material	Supplementary_Material_20160902003019.pdf
Peer-review Report	29990-Peer-review(s).pdf
Scientific Misconduct Check	29990-Scientific misconduct check.pdf
Scientific Editor Work List	29990-Scientific editor work list.pdf