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6/23/2017 1:45:17 AM | Browse: 907 | Download: 1602
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Received |
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2016-10-16 08:33 |
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Peer-Review Started |
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2016-10-19 15:38 |
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To Make the First Decision |
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2017-01-14 11:16 |
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Return for Revision |
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2017-01-16 16:38 |
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Revised |
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2017-02-24 19:27 |
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Second Decision |
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2017-03-13 10:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2017-03-24 10:39 |
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Articles in Press |
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2017-03-24 10:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-06-15 13:57 |
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Publish the Manuscript Online |
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2017-06-20 14:58 |
ISSN |
1949-8470 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Radiology, Nuclear Medicine & Medical Imaging |
Manuscript Type |
Observational Study |
Article Title |
Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study
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Manuscript Source |
Invited Manuscript |
All Author List |
Tamar M van Veenendaal, Dominique M IJff, Albert P Aldenkamp, Richard HC Lazeron, Paul AM Hofman, Anton JA de Louw, Walter H Backes and Jacobus FA Jansen |
Funding Agency and Grant Number |
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Corresponding Author |
Jacobus FA Jansen, PhD, Departments of Radiology and Nuclear Medicine, Maastricht University Medical Center, PO Box 5800, 6202 AZ, Maastricht, The Netherlands. jacobus.jansen@mumc.nl |
Key Words |
Antiepileptic drugs; Cognitive side effects; Brain networks; Resting state; Functional magnetic resonance imaging; Graph analysis |
Core Tip |
Slowed information processing is a commonly observed cognitive side-effect of antiepileptic drug (AED) treatment. We aimed to increase our insight in the neuronal mechanisms underlying this side-effect. Therefore, the relation between functional MR-acquired brain network measures, AED use, and cognitive function was investigated. No associations were found between information processing speed and graph measures, and only the four patients taking topiramate (with a high risk on cognitive side effects) showed aberrant network measures. The results suggest that alterations in functional brain network organization may be only subtle and measureable in patients with more severe cognitive side effects. |
Publish Date |
2017-06-20 14:58 |
Citation |
van Veenendaal TM, IJff DM, Aldenkamp AP, Lazeron RHC, Hofman PAM, de Louw AJA, Backes WH, Jansen JFA. Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study. World J Radiol 2017; 9(6): 287-294 |
URL |
http://www.wjgnet.com/1949-8470/full/v9/i6/287.htm |
DOI |
http://dx.doi.org/10.4329/wjr.v9.i6.287 |
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