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6/23/2017 1:45:17 AM | Browse: 826 | Download: 1292
Publication Name World Journal of Radiology
Manuscript ID 30764
Country Netherlands
Received
2016-10-16 08:33
Peer-Review Started
2016-10-19 15:38
To Make the First Decision
2017-01-14 11:16
Return for Revision
2017-01-16 16:38
Revised
2017-02-24 19:27
Second Decision
2017-03-13 10:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-03-24 10:39
Articles in Press
2017-03-24 10:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-06-15 13:57
Publish the Manuscript Online
2017-06-20 14:58
ISSN 1949-8470 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Observational Study
Article Title Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study
Manuscript Source Invited Manuscript
All Author List Tamar M van Veenendaal, Dominique M IJff, Albert P Aldenkamp, Richard HC Lazeron, Paul AM Hofman, Anton JA de Louw, Walter H Backes and Jacobus FA Jansen
Funding Agency and Grant Number
Corresponding Author Jacobus FA Jansen, PhD, Departments of Radiology and Nuclear Medicine, Maastricht University Medical Center, PO Box 5800, 6202 AZ, Maastricht, The Netherlands. jacobus.jansen@mumc.nl
Key Words Antiepileptic drugs; Cognitive side effects; Brain networks; Resting state; Functional magnetic resonance imaging; Graph analysis
Core Tip Slowed information processing is a commonly observed cognitive side-effect of antiepileptic drug (AED) treatment. We aimed to increase our insight in the neuronal mechanisms underlying this side-effect. Therefore, the relation between functional MR-acquired brain network measures, AED use, and cognitive function was investigated. No associations were found between information processing speed and graph measures, and only the four patients taking topiramate (with a high risk on cognitive side effects) showed aberrant network measures. The results suggest that alterations in functional brain network organization may be only subtle and measureable in patients with more severe cognitive side effects.
Publish Date 2017-06-20 14:58
Citation van Veenendaal TM, IJff DM, Aldenkamp AP, Lazeron RHC, Hofman PAM, de Louw AJA, Backes WH, Jansen JFA. Chronic antiepileptic drug use and functional network efficiency: A functional magnetic resonance imaging study. World J Radiol 2017; 9(6): 287-294
URL http://www.wjgnet.com/1949-8470/full/v9/i6/287.htm
DOI http://dx.doi.org/10.4329/wjr.v9.i6.287
Full Article (PDF) WJR-9-287.pdf
Full Article (Word) WJR-9-287.doc
Manuscript File 30764-Review.docx
Answering Reviewers 30764-Answering reviewers.pdf
Audio Core Tip 30764-Audio core tip.mp3
Biostatistics Review Certificate 30764-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 30764-Conflict-of-interest statement.pdf
Copyright License Agreement 30764-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) Informed_Consent_Statement_20161015205504.pdf
Institutional Review Board Approval Form or Document 30764-Institutional review board statement.pdf
Peer-review Report 30764-Peer-review(s).pdf
Scientific Misconduct Check 30764-Scientific misconduct check.pdf
Scientific Editor Work List 30764-Scientific editor work list.pdf