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6/14/2017 9:01:38 AM | Browse: 452 | Download: 1203
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Received |
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2016-12-15 15:15 |
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Peer-Review Started |
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2016-12-19 15:34 |
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To Make the First Decision |
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2017-03-27 11:52 |
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Return for Revision |
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2017-03-28 16:48 |
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Revised |
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2017-04-28 02:47 |
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Second Decision |
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2017-05-11 13:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2017-05-19 04:15 |
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Articles in Press |
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2017-05-19 04:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2017-05-26 08:45 |
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Publish the Manuscript Online |
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2017-06-14 07:52 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Angiotensin Ⅱ or epinephrine hemodynamic and metabolic responses in the liver of L-NAME induced hypertension and spontaneous hypertensive rats
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Debora Conte Kimura, Marcia Regina Nagaoka, Durval Rosa Borges and Maria Kouyoumdjian |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| FAPESP |
2011/13974-8 |
| CAPES |
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| Corresponding Author |
Maria Kouyoumdjian, PhD, Associate Professor of Biochemistry, Department of Biochemistry, Federal University of São Paulo, Experimental Hepatology Laboratory, Rua Botucatu 862 (Edifício José Leal Prado), São Paulo 04023-900, Brazil. mariak.bioq@epm.br |
| Key Words |
Epinephrine; Liver perfusion; Spontaneously hypertensive rat; Glucose; Angiotensin Ⅱ; L-NAME |
| Core Tip |
Angiotensin (Ang)Ⅱ and epinephrine (Epi) induce hemodynamic and metabolic responses in a normal liver. These responses are altered in different ways in two models of hypertension. We observed that inhibition of NO production seems to be involved in the hepatic hemodynamic and metabolic effects induced by Epi but not by AngⅡ. Furthermore, diminished glucose release induced by AngⅡ in spontaneously hypertensive rat is not related to glycogen content, but might be due to the glycogen phosphorylase activation by AngⅡ. |
| Publish Date |
2017-06-14 07:52 |
| Citation |
Kimura DC, Nagaoka MR, Borges DR, Kouyoumdjian M. Angiotensin II or epinephrine hemodynamic and metabolic responses in the liver of L-NAME induced hypertension and spontaneous hypertensive rats. World J Hepatol 2017; 9(17): 781-790 |
| URL |
http://www.wjgnet.com/1948-5182/full/v9/i17/781.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v9.i17.781 |
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