Publication Name	World Journal of Gastroenterology
Manuscript ID	32280
Country	Pakistan

Received	2016-12-30 09:22
Peer-Review Started	2017-01-03 16:43
To Make the First Decision	2017-02-10 08:46
Return for Revision	2017-02-13 13:07
Revised	2017-02-23 00:00
Second Decision	2017-03-09 13:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-03-15 09:57
Articles in Press	2017-03-15 09:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-03-23 14:05
Publish the Manuscript Online	2017-04-06 18:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Immunology
Manuscript Type	Minireviews
Article Title	Indoleamine 2,3-dioxygenase: As a potential prognostic marker and immunotherapeutic target for hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Kashif Asghar, Asim Farooq, Bilal Zulfiqar and Muhammad Usman Rashid
Funding Agency and Grant Number
Corresponding Author	Dr. Kashif Asghar, Department of Basic Sciences Research, Shaukat Khanum Memorial Cancer Hospital and Research Centre, 7-A Block R-3, Johar Town, Lahore 54000, Pakistan. kashifasghar@skm.org.pk
Key Words	Hepatocellular carcinoma; Hepatitis C virus, Hepatitis B virus; Indoleamine 2,3-dioxygenase
Core Tip	Indoleamine 2,3-dioxygenase (IDO) is an immunosuppressive enzyme which mediates tumor immune escape in hepatocellular carcinoma (HCC). IDO up-regulation in HCC may lead to recruitment of regulatory T-cells into tumor microenvironment and therefore inhibit local immune responses and promote metastasis. IDO inhibitors as adjuvant therapeutic agents may have clinical implications in HCC.
Publish Date	2017-04-06 18:30
Citation	Asghar K, Farooq A, Zulfiqar B, Rashid MU. Indoleamine 2,3-dioxygenase: As a potential prognostic marker and immunotherapeutic target for hepatocellular carcinoma. World J Gastroenterol 2017; 23(13): 2286-2293
URL	http://www.wjgnet.com/1007-9327/full/v23/i13/2286.htm
DOI	http://dx.doi.org/10.3748/wjg.v23.i13.2286

Full Article (PDF)	WJG-23-2286.pdf
Full Article (Word)	WJG-23-2286.doc
Manuscript File	32280-Review.docx
Answering Reviewers	32280-Answering reviewers.pdf
Audio Core Tip	32280-Audio core tip.wma
Conflict-of-Interest Disclosure Form	32280-Conflict-of-interest statement.pdf
Copyright License Agreement	32280-Copyright assignment.pdf
Peer-review Report	32280-Peer-reivew(s).pdf
Scientific Misconduct Check	32280-Scientific misconduct check.pdf
Scientific Editor Work List	32280-Scientific editor work list.pdf