Publication Name	World Journal of Orthopedics
Manuscript ID	33734
Country	Thailand

Received	2017-02-28 09:38
Peer-Review Started	2017-02-28 16:38
To Make the First Decision	2017-05-08 15:30
Return for Revision	2017-05-09 17:31
Revised	2017-06-01 11:33
Second Decision	2017-06-22 02:12
Accepted by Journal Editor-in-Chief	2017-06-23 01:13
Accepted by Company Editor-in-Chief	2017-07-03 02:35
Articles in Press	2017-07-03 02:35
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-09-07 03:19
Publish the Manuscript Online	2017-09-13 00:54

ISSN	2218-5836 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Mesenchymal stem cells for cartilage regeneration in osteoarthritis
Manuscript Source	Invited Manuscript
All Author List	Baldur Kristjánsson and Sittisak Honsawek
Funding Agency and Grant Number
Corresponding Author	Sittisak Honsawek, MD, PhD, Department of Orthopaedics, Vinai Parkpian Orthopaedic Research Center, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Rama IV Road, Patumwan, Bangkok 10330, Thailand. sittisak.h@chula.ac.th
Key Words	Cartilage; Intra-articular injection; Mesenchymal stem cells; Osteoarthritis; Regeneration
Core Tip	There are several published reviews of the role of multipotent stromal cells in osteoarthritis (OA) of the knee. However, there is also need for additional current therapeutic options and clinical trials of multipotent stromal cells for OA. We review additional therapeutic potentials of mesenchymal stem cells in knee OA using either autogenous or allogenic cells. Direct intra-articular injections of cells in suspension become a delivery method, being both relatively simple and cost effective compared to major surgical procedures. The amount of cells injected is a critical factor; higher numbers of cells resulting in greater pain reduction and increased cartilage volume.
Publish Date	2017-09-13 00:54
Citation	Kristjánsson B, Honsawek S. Mesenchymal stem cells for cartilage regeneration in osteoarthritis. World J Orthop 2017; 8(9): 674-680
URL	http://www.wjgnet.com/2218-5836/full/v8/i9/674.htm
DOI	http://dx.doi.org/10.5312/wjo.v8.i9.674

Full Article (PDF)	WJO-8-674.pdf
Full Article (Word)	WJO-8-674.doc
Manuscript File	33734-Review.doc
Answering Reviewers	33734-Answering reviewers.pdf
Audio Core Tip	33734-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	33734-Conflict-of-interest statement.pdf
Copyright License Agreement	33734-Copyright assignment.pdf
Peer-review Report	33734-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	33734-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	33734-Scientific misconduct check.pdf
Scientific Editor Work List	33734-Scientific editor work list.pdf