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8/18/2017 5:42:43 AM | Browse: 345 | Download: 442
Publication Name World Journal of Experimental Medicine
Manuscript ID 34092
Country of Manuscript Source Brazil
Received
2017-03-27 08:31
Peer-Review Started
2017-03-28 18:27
To Make the First Decision
2017-05-08 15:30
Return for Revision
2017-05-09 17:42
Revised
2017-06-11 11:21
Second Decision
2017-06-22 02:12
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-07-03 02:36
Articles in Press
2017-07-03 02:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-08-15 09:28
Publish the Manuscript Online
2017-08-18 02:46
ISSN 2220-315x (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Medicine, Research and Experimental
Manuscript type Review
Article Title Surgical and immune reconstitution murine models in bone marrow research: Potential for exploring mechanisms in sepsis, trauma and allergy
Manuscript Source Invited Manuscript
All Author List Pedro Xavier-Elsas, Renato Nunes Ferreira and Maria Ignez C Gaspar-Elsas
Funding Agency and Grant Number
Correspondence To Pedro Xavier-Elsas, MD, PhD, Associate Professor, Department of Immunology, Instituto de Microbiologia Paulo de Góes, Universidade Federal do Rio de Janeiro, Bloco I, Room I-2-066, Rio de Janeiro 21941-590, Brazil. pxelsas@micro.ufrj.br
Keywords Bone-marrow; Trauma; Repair; Transplantation; Surgery
Core Tip Bone-marrow generates multiple cell types which may play important roles in repair at distant sites. The use of surgical models in the characterization of this emerging function has hitherto been limited. Surgical strategies allow nevertheless the experimenter to predetermine the site, timing, severity and invasiveness of injury; to add or remove aggravating factors (such as infection and defects in immunity) in controlled ways; and to manipulate the context of repair, including reconstitution with selected immune cell subpopulations. Here we review surgical models with great potential for exploring bone-marrow responses to injury, inflammation and infection.
Publish Date 2017-08-18 02:46
Citation Xavier-Elsas P, Ferreira RN, Gaspar-Elsas MIC. Surgical and immune reconstitution murine models in bone marrow research: Potential for exploring mechanisms in sepsis, trauma and allergy. World J Exp Med 2017; 7(3): 58-77
Url http://www.wjgnet.com/2220-315X/full/v7/i3/58.htm
DOI http://dx.doi.org/10.5493/wjem.v7.i3.58
Full Article (PDF) WJEM-7-58.pdf
Full Article (Word) WJEM-7-58.doc
Manuscript File 34092-Review.docx
Answering Reviewers 34092-Answering reviewers.pdf
Audio Core Tip 34092-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 34092-Conflict-of-interest statement.pdf
Copyright License Agreement 34092-Copyright assignment.pdf
Peer-review Report 34092-Peer-review(s).pdf
Scientific Misconduct Check 34092-Scientific misconduct check.pdf
Scientific Editor Work List 34092-Scientific editor work list.pdf