Publication Name	World Journal of Respirology
Manuscript ID	34314
Country	Portugal

Received	2017-05-01 12:08
Peer-Review Started	2017-05-03 11:33
First Decision by Editorial Office Director
Return for Revision	2017-05-23 09:25
Revised	2017-06-05 12:50
Publication Fee Transferred
Second Decision by Editor	2017-06-22 02:05
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2017-07-03 02:43
Articles in Press	2017-07-03 02:43
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-07-18 08:34
Publish the Manuscript Online	2017-07-21 02:55

ISSN	2218-6255 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Respiratory System
Manuscript Type	Frontier
Article Title	Is the determination of ctDNA a scientific “spy” that foresees cancer?
Manuscript Source	Invited Manuscript
All Author List	Joana Espiga de Macedo and Manuela Machado
Funding Agency and Grant Number
Corresponding Author	Joana Espiga de Macedo, MD, Consultant of Medical Oncology, Department of Medical Oncology of Centro Hospitalar de Entre Douro e Vouga, Rua Dr. Cândido de Pinho, 4520-211 Santa Maria Da Feira, Portugal. joana.macedo@chedv.min-saude.pt
Key Words	Tumour biopsies; Liquid biopsies; Circulating tumour DNA; Precision cancer medicine
Core Tip	With the increase development of molecular medicine we may further change our clinical rational to a precise cancer medicine rational way. Consequently, we may improve the quality of life of our patients, with less toxicity, more cost-effectiveness decisions and above all improve response rate and survival. Defining the complete genomic “picture” of all cancerous lesions, in the near future as a standard of care, will require all genetic information concerning each individual cancer.
Publish Date	2017-07-21 02:55
Citation	de Macedo JE, Machado M. Is the determination of ctDNA a scientific “spy” that foresees cancer? World J Respirol 2017; 7(2): 35-38
URL	http://www.wjgnet.com/2218-6255/full/v7/i2/35.htm
DOI	http://dx.doi.org/10.5320/wjr.v7.i2.35

Full Article (PDF)	WJR-7-35.pdf
Full Article (Word)	WJR-7-35.doc
Manuscript File	34314-Review.docx
Answering Reviewers	34314-Answering reviewers.pdf
Audio Core Tip	34314-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	34314-Conflict-of-interest statement.pdf
Copyright License Agreement	34314-Copyright assignment.pdf
Supplementary Material	34314_table SPY.docx
Peer-review Report	34314-Peer-review(s).pdf
Scientific Misconduct Check	34314-Scientific misconduct check.pdf
Scientific Editor Work List	34314-Scientific editor work list.pdf