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11/27/2017 8:30:59 AM | Browse: 844 | Download: 870
Publication Name World Journal of Nephrology
Manuscript ID 35013
Country/Territory Saudi Arabia
Received
2017-06-27 02:24
Peer-Review Started
2017-06-28 22:21
To Make the First Decision
2017-09-04 00:50
Return for Revision
2017-09-04 03:07
Revised
2017-09-12 17:21
Second Decision
2017-09-14 07:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2017-11-02 04:18
Articles in Press
2017-11-02 04:18
Publication Fee Transferred
2017-11-08 10:20
Edit the Manuscript by Language Editor
Typeset the Manuscript
2017-11-24 02:22
Publish the Manuscript Online
2017-11-27 06:08
ISSN 2220-6124 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Case Report
Article Title Atypical hemolytic-uremic syndrome due to complement factor I mutation
Manuscript Source Unsolicited Manuscript
All Author List Abdullah H Almalki, Laila F Sadagah, Mohammed Qureshi, Hatim Maghrabi, Abdulrahman Algain and Ahmed Alsaeed
Funding Agency and Grant Number
Corresponding Author Abdullah H Almalki, MD, Assistant Professor, Staff Physician, Nephrology, King Saud Bin Abdulaziz University for Health Sciences, Nephrology Section, Department of Medicine, King Abdulaziz Medical City, Western Region, PO Box 9515, Jeddah 21423, Saudi Arabia. malkia02@ngha.med.sa
Key Words Atypical hemolytic-uremic syndrome; Thrombotic microangiopathy; Complement factor I mutation
Core Tip Atypical hemolytic-uremic syndrome (aHUS) is a rare disorder. In some cases, complement mutation can be identified. The most common cases involved mutations of genes for complement factor H and membrane co-factor protein, whereas rare cases were linked to complement factor I (CFI) mutation. We here describe the first case of aHUS due to CFI mutation in Saudi Arabia. Our case presented with interesting characteristics including late recovery of kidney failure from dialysis upon initiation of eculizumab and persistent hematologic and renal remissions despite discontinuation of eculizumab.
Publish Date 2017-11-27 06:08
Citation Almalki AH, Sadagah LF, Qureshi M, Maghrabi H, Algain A, Alsaeed A. Atypical hemolytic-uremic syndrome due to complement factor I mutation. World J Nephrol 2017; 6(6): 243-250
URL http://www.wjgnet.com/2220-6124/full/v6/i6/243.htm
DOI http://dx.doi.org/10.5527/wjn.v6.i6.243
Full Article (PDF) WJN-6-243.pdf
Full Article (Word) WJN-6-243.doc
Manuscript File 35013-Review.docx
Answering Reviewers 35013-Answering reviewers.pdf
Audio Core Tip 35013-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 35013-Conflict-of-interest statement.pdf
Copyright License Agreement 35013-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s) 35013-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 35013-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 35013-Language certificate.pdf
Peer-review Report 35013-Peer-review(s).pdf
Scientific Editor Work List 35013-Scientific editor work list.pdf