Publication Name	World Journal of Nephrology
Manuscript ID	35013
Country	Saudi Arabia

Received	2017-06-27 02:24
Peer-Review Started	2017-06-28 22:21
To Make the First Decision	2017-09-04 00:50
Return for Revision	2017-09-04 03:07
Revised	2017-09-12 17:21
Second Decision	2017-09-14 07:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2017-11-02 04:18
Articles in Press	2017-11-02 04:18
Publication Fee Transferred	2017-11-08 10:20
Edit the Manuscript by Language Editor
Typeset the Manuscript	2017-11-24 02:22
Publish the Manuscript Online	2017-11-27 06:08

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Urology & Nephrology
Manuscript Type	Case Report
Article Title	Atypical hemolytic-uremic syndrome due to complement factor I mutation
Manuscript Source	Unsolicited Manuscript
All Author List	Abdullah H Almalki, Laila F Sadagah, Mohammed Qureshi, Hatim Maghrabi, Abdulrahman Algain and Ahmed Alsaeed
Funding Agency and Grant Number
Corresponding Author	Abdullah H Almalki, MD, Assistant Professor, Staff Physician, Nephrology, King Saud Bin Abdulaziz University for Health Sciences, Nephrology Section, Department of Medicine, King Abdulaziz Medical City, Western Region, PO Box 9515, Jeddah 21423, Saudi Arabia. malkia02@ngha.med.sa
Key Words	Atypical hemolytic-uremic syndrome; Thrombotic microangiopathy; Complement factor I mutation
Core Tip	Atypical hemolytic-uremic syndrome (aHUS) is a rare disorder. In some cases, complement mutation can be identified. The most common cases involved mutations of genes for complement factor H and membrane co-factor protein, whereas rare cases were linked to complement factor I (CFI) mutation. We here describe the first case of aHUS due to CFI mutation in Saudi Arabia. Our case presented with interesting characteristics including late recovery of kidney failure from dialysis upon initiation of eculizumab and persistent hematologic and renal remissions despite discontinuation of eculizumab.
Publish Date	2017-11-27 06:08
Citation	Almalki AH, Sadagah LF, Qureshi M, Maghrabi H, Algain A, Alsaeed A. Atypical hemolytic-uremic syndrome due to complement factor I mutation. World J Nephrol 2017; 6(6): 243-250
URL	http://www.wjgnet.com/2220-6124/full/v6/i6/243.htm
DOI	http://dx.doi.org/10.5527/wjn.v6.i6.243

Full Article (PDF)	WJN-6-243.pdf
Full Article (Word)	WJN-6-243.doc
Manuscript File	35013-Review.docx
Answering Reviewers	35013-Answering reviewers.pdf
Audio Core Tip	35013-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	35013-Conflict-of-interest statement.pdf
Copyright License Agreement	35013-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	35013-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	35013-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	35013-Language certificate.pdf
Peer-review Report	35013-Peer-review(s).pdf
Scientific Editor Work List	35013-Scientific editor work list.pdf