Publication Name	World Journal of Gastroenterology
Manuscript ID	39018
Country	Brazil

Received	2018-04-04 00:37
Peer-Review Started	2018-04-04 09:15
To Make the First Decision	2018-04-27 02:25
Return for Revision	2018-04-27 08:32
Revised	2018-05-23 18:59
Second Decision	2018-06-15 08:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2018-06-16 06:03
Articles in Press	2018-06-16 06:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2018-07-09 07:51
Publish the Manuscript Online	2018-07-12 23:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Liver transplantation and alcoholic liver disease: History, controversies, and considerations
Manuscript Source	Invited Manuscript
All Author List	Cláudio Augusto Marroni, Alfeu de Medeiros Fleck Jr, Sabrina Alves Fernandes, Lucas Homercher Galant, Marcos Mucenic, Mario Henrique de Mattos Meine, Guilherme Mariante-Neto and Ajacio Bandeira de Mello Brandão
Funding Agency and Grant Number
Corresponding Author	Cláudio Augusto Marroni, MD, PhD, Professor, Graduate Program in Medicine: Hepatology, Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Rua José Kanan Aranha, 102, Jardim Isabel, Porto Alegre 90430-080, RS, Brazil. nmarroni@terra.com.br
Key Words	Alcoholic liver disease; Alcoholic hepatitis; Alcoholic cirrhosis; Alcoholism; Liver transplantation; Alcoholic recurrence; Controversies; Alcoholic abstinence; Relapse; Selection criteria
Core Tip	Alcohol consumption accounts for 3.8% of annual global mortality worldwide. Cirrhosis is a common complication of alcoholic liver disease (ALD) and when end-stage liver disease is reached, the only chance of survival is liver transplantation (LT). There are contro­versies and ethical dilemmas associated with LT for ALD. This study reviews the history and controversies and considers the development of, indications for, and outcomes of LT in ALD, including severe acute alcoholic hepatitis. Relapse, therapeutic options, and outcomes are emphasized.
Publish Date	2018-07-12 23:54
Citation	Marroni CA, Fleck Jr AM, Fernandes SA, Galant LH, Mucenic M, de Mattos Meine MH, Mariante-Neto G, Brandão ABM. Liver transplantation and alcoholic liver disease: history, controversies and considerations. World J Gastroenterol 2018; 24(26): 2785-2805
URL	http://www.wjgnet.com/1007-9327/full/v24/i26/2785.htm
DOI	http://dx.doi.org/10.3748/wjg.v24.i26.2785

Full Article (PDF)	WJG-24-2785.pdf
Manuscript File	39018-Review.doc
Answering Reviewers	39018-Answering reviewers.pdf
Audio Core Tip	39018-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	39018-Conflict-of-interest statement.pdf
Copyright License Agreement	39018-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	39018-Language certificate.pdf
Peer-review Report	39018-Peer-review(s).pdf
Scientific Misconduct Check	39018-Scientific misconduct check.pdf
Scientific Editor Work List	39018-Scientific editor work list.pdf