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9/4/2018 3:36:03 AM | Browse: 780 | Download: 1871
Publication Name World Journal of Transplantation
Manuscript ID 39072
Country United States
Received
2018-04-11 02:13
Peer-Review Started
2018-04-11 03:39
First Decision by Editorial Office Director
2018-04-29 01:38
Return for Revision
2018-05-03 07:33
Revised
2018-05-21 21:04
Publication Fee Transferred
Second Decision by Editor
2018-05-30 12:29
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2018-05-31 04:06
Articles in Press
2018-05-31 04:06
Edit the Manuscript by Language Editor
Typeset the Manuscript
2018-08-06 01:44
Publish the Manuscript Online
2018-08-09 08:05
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Study
Article Title Kidney transplantation in older recipients: Preemptive high KDPI kidney vs lower KDPI kidney after varying dialysis vintage
Manuscript Source Invited Manuscript
All Author List Bhavna Chopra and Kalathil K Sureshkumar
Funding Agency and Grant Number
Corresponding Author Kalathil K Sureshkumar, MD, Associate Professor, Division of Nephrology and Hypertension, Department of Medicine, Allegheny General Hospital, Allegheny Health Network, 320 East North Avenue, Pittsburgh, PA 15212, United States. kalathil.sureshkumar@ahn.org
Key Words Preemptive kidney transplantation; Kidney donor profile index; Dialysis vintage; Kidney transplant outcomes; Older recipients; Waiting list
Core Tip Increasing waiting-time for deceased donor kidney (DDK) transplantation adversely impacts older patients disproportionately. Dialysis vintage and transplantation of “marginal kidneys” are associated with inferior post-transplant outcomes. Using OPTN/United Network for Organ Sharing database from 2001-2015, we compared the outcomes of preemptive transplantation of marginal [kidney donor profile index (KDPI) ≥ 85%] DDKs compared to transplanting better quality DDKs (KDPI 35%-84%) after being on dialysis for 1-4 and 4-8 years in patient > 60 years old. Preemptive transplantation of marginal kidneys provided non-inferior graft and patient outcomes compared to transplanting better quality kidneys in older patients on maintenance dialysis. Early transplantation could also provide quality of life and cost benefits.
Publish Date 2018-08-09 08:05
Citation Chopra B, Sureshkumar KK. Kidney transplantation in older recipients: Preemptive high KDPI kidney vs lower KDPI kidney after varying dialysis vintage. World J Transplant 2018; 8(4): 102-109
URL http://www.wjgnet.com/2220-3230/full/v8/i4/102.htm
DOI http://dx.doi.org/10.5500/wjt.v8.i4.102
Full Article (PDF) WJT-8-102.pdf
Full Article (Word) WJT-8-102.doc