Publication Name	World Journal of Nephrology
Manuscript ID	39724
Country	Ireland

Received	2018-05-07 00:33
Peer-Review Started	2018-05-07 01:51
To Make the First Decision	2018-05-24 23:53
Return for Revision	2018-05-25 07:45
Revised	2018-08-05 19:04
Second Decision	2018-08-30 08:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-08-30 17:43
Articles in Press	2018-08-30 17:43
Publication Fee Transferred
Edit the Manuscript by Language Editor	2018-09-09 01:40
Typeset the Manuscript	2018-10-10 01:51
Publish the Manuscript Online	2018-10-10 08:42

ISSN	2220-6124 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Urology & Nephrology
Manuscript Type	Minireviews
Article Title	Oral alkali therapy and the management of metabolic acidosis of chronic kidney disease: a narrative literature review
Manuscript Source	Unsolicited Manuscript
All Author List	Adeel Rafi Ahmed and David Lappin
Funding Agency and Grant Number
Corresponding Author	Adeel Rafi Ahmed, MBChB, MRCP, Staff Physician, Department of Nephrology, University Hospital Galway, Newcastle Road, Galway H91YR1, Ireland. adeel.r.ahmed@gmail.com
Key Words	Chronic metabolic acidosis; Chronic kidney disease; Oral sodium bicarbonate; Oral alkali therapy; Health economics; Serum bicarbonate
Core Tip	Chronic metabolic acidosis contributes to the progression of chronic kidney disease (CKD). We summarise and analyse current evidence regarding the management of the metabolic acidosis of CKD, as well as the potential benefits and adverse effects. We also offer novel therapeutic guidelines for clinicians, which include the most evidence-based range to maintain serum bicarbonate in the CKD patient population.
Publish Date	2018-10-10 08:42
Citation	Ahmed AR, Lappin D. Oral alkali therapy and the management of metabolic acidosis of chronic kidney disease: A narrative literature review. World J Nephrol 2018; 7(6): 117-122
URL	http://www.wjgnet.com/2220-6124/full/v7/i6/117.htm
DOI	http://dx.doi.org/10.5527/wjn.v7.i6.117

Full Article (PDF)	WJN-7-117.pdf
Full Article (Word)	WJN-7-117.doc
Manuscript File	39724-Review.docx
Answering Reviewers	39724-Answering reviewers.pdf
Audio Core Tip	39724-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	39724-Conflict-of-interest statement.pdf
Copyright License Agreement	39724-Copyright license agreement.pdf
Peer-review Report	39724-Peer-review(s).pdf
Scientific Misconduct Check	39724-Scientific misconduct check.pdf
Scientific Editor Work List	39724-Scientific editor work list.pdf