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9/4/2018 3:35:57 AM | Browse: 739 | Download: 1089
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Received |
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2018-05-19 03:56 |
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Peer-Review Started |
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2018-05-19 12:34 |
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To Make the First Decision |
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2018-06-15 02:28 |
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Return for Revision |
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2018-06-19 01:07 |
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Revised |
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2018-07-03 16:26 |
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Second Decision |
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2018-07-13 09:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-07-16 05:20 |
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Articles in Press |
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2018-07-16 05:20 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2018-07-22 15:52 |
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Typeset the Manuscript |
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2018-08-01 08:19 |
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Publish the Manuscript Online |
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2018-08-07 07:57 |
| ISSN |
2150-5349 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Blood glucose response after oral intake of lactulose in healthy volunteers: A randomized, controlled, cross-over study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jasmin Steudle, Christiane Schön, Manfred Wargenau, Lioba Pauly, Susann Schwejda-Guettes, Barbara Gaigg, Angelika Kuchinka-Koch and John F Stover |
| Funding Agency and Grant Number |
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| Corresponding Author |
John F Stover, MD, Fresenius Kabi Deutschland GmbH, Borkenberg 14, Oberursel 61440, Germany. john.stover@fresenius-kabi.com |
| Key Words |
Lactulose; Functional food ingredient; Sugar substitute; Blood glucose concentration |
| Core Tip |
Lactulose can be used as a functional food ingredient. During manufacturing as liquid or crystalline formulation, impurities with different sugars occur. Lactulose may also be consumed by people with impaired glucose tolerance, including diabetics. For these consumers, it is of interest whether the described carbohydrate impurities may increase blood glucose levels after ingestion. This study was performed to investigate possible changes of blood glucose levels after oral intake of 10 g and 20 g of liquid and crystalline lactulose in healthy subjects. The small amounts of carbohydrate impurities did not influence blood glucose levels, indicating potential applicability to people with impaired glucose tolerance. |
| Publish Date |
2018-08-07 07:57 |
| Citation |
Steudle J, Schön C, Wargenau M, Pauly L, Schwejda-Güttes S, Gaigg B, Kuchinka-Koch A, Stover JF. Blood glucose response after oral intake of lactulose in healthy volunteers: A randomized, controlled, cross-over study. World J Gastrointest Pharmacol Ther 2018; 9(3): 22-30 |
| URL |
http://www.wjgnet.com/2150-5349/full/v9/i3/22.htm |
| DOI |
http://dx.doi.org/10.4292/wjgpt.v9.i3.22 |
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