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12/26/2018 3:14:42 AM | Browse: 588 | Download: 1653
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Received |
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2018-07-04 02:42 |
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Peer-Review Started |
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2018-07-05 01:53 |
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First Decision by Editorial Office Director |
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2018-07-24 16:57 |
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Return for Revision |
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2018-07-31 02:45 |
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Revised |
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2018-08-05 13:06 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-08-31 07:37 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-08-31 21:41 |
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Articles in Press |
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2018-08-31 21:41 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-10-09 08:05 |
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Publish the Manuscript Online |
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2018-10-15 12:09 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Basic Study |
| Article Title |
miR-122-5p as a novel biomarker for alpha-fetoprotein-producing gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Suguru Maruyama, Shinji Furuya, Kensuke Shiraishi, Hiroki Shimizu, Hidenori Akaike, Naohiro Hosomura, Yoshihiko Kawaguchi, Hidetake Amemiya, Hiromichi Kawaida, Makoto Sudo, Shingo Inoue, Hiroshi Kono and Daisuke Ichikawa |
| Funding Agency and Grant Number |
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| Corresponding Author |
Daisuke Ichikawa, MD, PhD, Professor, First Department of Surgery, Faculty of Medicine University of Yamanashi, 1110 Shimokato, Chuou, Yamanashi 409-3898, Japan. dichikawa@yamanashi.ac.jp |
| Key Words |
Gastric cancer; Alpha-fetoprotein; Alpha-fetoprotein producing gastric cancer; MicroRNA; miR-122-5p |
| Core Tip |
We examined the microRNAs (miRNA) expression in alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC) tissue samples using a comprehensive miRNA array-based approach, and also investigated the clinical utility of the identified AFPGC-specific miRNAs. We found the expression of miR-122-5p was significantly higher in the AFPGC tissues and plasma samples. Moreover, tissue miR-122-5p expression levels exhibited a stronger correlation with malignant potential than plasma AFP level in AFPGC patients. miR-122-5p might be a useful biomarker for early detection and disease monitoring in AFPGC. |
| Publish Date |
2018-10-15 12:09 |
| Citation |
Maruyama S, Furuya S, Shiraishi K, Shimizu H, Akaike H, Hosomura N, Kawaguchi Y, Amemiya H, Kawaida H, Sudo M, Inoue S, Kono H, Ichikawa D. miR-122-5p as a novel biomarker for alpha-fetoprotein-producing gastric cancer. World J Gastrointest Oncol 2018; 10(10): 344-350
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| URL |
http://www.wjgnet.com/1948-5204/full/v10/i10/344.htm |
| DOI |
http://dx.doi.org/10.4251/wjgo.v10.i10.344 |
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