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1/27/2019 7:53:50 AM | Browse: 285 | Download: 126
Publication Name World Journal of Gastroenterology
Manuscript ID 40633
Country of Manuscript Source India
2018-07-26 05:56
Peer-Review Started
2018-07-26 08:07
To Make the First Decision
2018-10-08 03:59
Return for Revision
2018-10-09 06:58
2018-12-07 06:27
Second Decision
2018-12-14 10:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-15 02:26
Articles in Press
2018-12-15 02:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-25 02:16
Publish the Manuscript Online
2019-01-26 11:40
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Minireviews
Article Title Differentiating Crohn’s disease from intestinal tuberculosis
Manuscript Source Invited Manuscript
All Author List Saurabh Kedia, Prasenjit Das, Kumble Seetharama Madhusudhan, Siddhartha Dattagupta, Raju Sharma, Peush Sahni, Govind K Makharia and Vineet Ahuja
Funding Agency and Grant Number
Correspondence To Saurabh Kedia, MD, Assistant Professor, Department of Gastroenterology, All India Institute of Medical Sciences, Room No 3066, Third Floor, Teaching Block, New Delhi 110029, India. dr.saurabhkedia@yahoo.com
Keywords Crohn's disease; Intestinal tuberculosis; Endoscopy; Computed tomographic enterography; Granuloma
Core Tip There is a constant challenge of differentiating Crohn’s disease (CD) from intestinal tuberculosis, especially with the increasing burden of inflammatory bowel disease in tuberculosis-endemic areas. Caseation necrosis on biopsy, positive acid-fast bacillus smear/culture, and necrotic lymph node on computed tomography (CT) are the only differentiating features with 100% specificity, though are limited by poor sensitivity. Multi-parametric models have their own limitations and a therapeutic trial of anti-tubercular therapy is often required. Upcoming markers include the latest Bayesian meta-analysis, enumeration of peripheral blood T-regulatory cells, and updated CT based predictive score. Therapeutic trial is associated with a delay in CD diagnosis, and better modalities/biomarkers are required for improved differentiation and reduction in the need for anti-tubercular therapy trial.
Publish Date 2019-01-26 11:40
Citation Kedia S, Das P, Madhusudhan KS, Dattagupta S, Sharma R, Sahni P, Makharia G, Ahuja V. Differentiating Crohn’s disease from intestinal tuberculosis. World J Gastroenterol 2019; 25(4): 418-432
Url https://www.wjgnet.com/1007-9327/full/v25/i4/418.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i4.418
Full Article (PDF) WJG-25-418.pdf
Full Article (Word) WJG-25-418.docx
Manuscript File 40633-Review.docx
Answering Reviewers 40633-Answering reviewers.pdf
Audio Core Tip 40633-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 40633-Conflict-of-interest statement.pdf
Copyright License Agreement 40633-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 40633-Non-Native-Speakers-of-English-Editing-Certificate-revision.docx
Peer-review Report 40633-Peer-review(s).pdf
Scientific Misconduct Check 40633-Scientific misconduct check.pdf
Scientific Editor Work List 40633-Scientific editor work list.pdf