BPG is committed to discovery and dissemination of knowledge
Featured Articles
12/26/2018 3:20:15 AM | Browse: 70 | Download: 43
Publication Name World Journal of Clinical Cases
Manuscript ID 42131
Country of Manuscript Source Croatia
Received
2018-09-10 07:10
Peer-Review Started
2018-09-10 07:31
To Make the First Decision
2018-10-12 00:26
Return for Revision
2018-10-12 07:39
Revised
2018-10-17 18:53
Second Decision
2018-11-07 09:36
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-11-07 22:30
Articles in Press
2018-11-07 22:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-11-13 21:31
Typeset the Manuscript
2018-12-04 06:26
Publish the Manuscript Online
2018-12-24 01:07
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7901 Stoneridge Drive, Suite 501, Pleasanton, CA 94588, USA
Website http://www.wjgnet.com
Specialty Neurosciences
Manuscript Type Randomized Clinical Trial
Article Title Effect of clonidine on the cutaneous silent period during spinal anesthesia
Manuscript Source Invited Manuscript
All Author List Sandra Graf Zupcic, Miroslav Zupcic, Viktor Duzel, Tatjana Šimurina, Milan Milošević, Silvio Basic, Vladimira Vuletic and Leonardo Kapural
Funding Agency and Grant Number
Correspondence To Miroslav Zupcic, MD, PhD, Assistant Professor, Clinic of Anesthesiology and Intensive Care Medicine, Clinical Hospital Centre Rijeka, Kresimirova Ulica 42, Rijeka 51000, Croatia. miro_zupcic@yahoo.com
Keywords Clonidine; Local anesthetics; Nerve fibers; Spinal anesthesia; Reflex
Core Tip Cutaneous silent period (CSP) is an oligo¬synaptic spinal inhibitory reflex. The results of our study show that intrathecal administration of levobupivacaine with added clonidine, in comparison to levobupivacaine alone, yields a significantly shorter CSP and a significantly longer CSP latency during block regression following subarachnoid block (SAB) application. Accordingly, we can conclude that during SAB regression, a small dose of intrathecally administered clonidine ameliorates the inhibitory tonus and accelerates the conduction in the oligosynaptic spinal circuit.
Publish Date 2018-12-24 01:07
Citation Graf Zupcic S, Zupcic M, Duzel V, Šimurina T, Milošević M, Basic S, Vuletic V, Kapural L. Effect of clonidine on the cutaneous silent period during spinal anesthesia. World J Clin Cases 2018; 6(16): 1136-1145
Url https://www.wjgnet.com/2307-8960/full/v6/i16/1136.htm
DOI https://dx.doi.org/10.12998/wjcc.v6.i16.1136
Full Article (PDF) WJCC-6-1136.pdf
Full Article (Word) WJCC-6-1136.doc
Revised Manuscript 42131-Review.doc
Peer-review Report 42131-Peer-review(s).pdf
Answering Reviewers 42131-Answering reviewers.pdf
Scientific Misconduct Check 42131-Scientific misconduct check.pdf
Scientific Editor Work List 42131-Scientific editor work list.pdf
Audio Core Tip 42131-Audio core tip.mp3
Biostatistics Review Certificate 42131-Biostatistics statement.pdf
Clinical Trial Registration Statement 42131-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 42131-Conflict-of-interest statement.pdf
Copyright License Agreement 42131-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 42131-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 42131-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 42131-Language certificate.pdf