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12/26/2018 3:20:17 AM | Browse: 119 | Download: 84
Publication Name World Journal of Stem Cells
Manuscript ID 42244
Country of Manuscript Source Mexico
Received
2018-09-13 02:54
Peer-Review Started
2018-09-13 12:50
To Make the First Decision
2018-10-08 03:40
Return for Revision
2018-10-09 10:16
Revised
2018-10-20 03:47
Second Decision
2018-11-14 11:19
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-11-16 05:57
Articles in Press
2018-11-16 05:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-11-27 01:41
Typeset the Manuscript
2018-12-13 04:27
Publish the Manuscript Online
2018-12-25 02:53
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Cell Biology
Manuscript type Minireviews
Article Title Cancer stem cell impact on clinical oncology
Manuscript Source Invited Manuscript
All Author List Mariel Esperanza Toledo-Guzmán, Gabriele D Bigoni-Ordóñez, Miguel Ibáñez-Hernández and Elizabeth Ortiz-Sanchez
Funding Agency and Grant Number
Correspondence To Elizabeth Ortiz-Sanchez, MD, PhD, Academic Research, Professor, Research Scientist, Senior Researcher, Subdirección de Investigación Básica, Instituto Nacional de Cancerología, Av San Fernando 22, Colonia Sección XVI, Mexico City 14080, Mexico. elinfkb@yahoo.com.mx
Keywords Cancer; Targeted therapy; Clinical outcome; Drug resistance; Cancer stem cells
Core Tip Tumor heterogeneity can explain the presence of cells that display high tumorigenic capacity along with chemo- and radio-resistance properties. These cells, identified as cancer stem cells (CSCs), are par­tially responsible for recurrence and tumor progression. Most tumors follow the CSC model, which indicates the existence of a subset of highly tumorigenic cells. This has been shown to be the case for several patients with several types of tumors. In this review, we focus on the phenotypes used for the study and identification of CSCs from human samples, as well as promising strategies to target CSCs.
Publish Date 2018-12-25 02:53
Citation Toledo-Guzmán ME, Bigoni-Ordóñez GD, Ibáñez Hernández M, Ortiz-Sánchez E. Cancer stem cell impact on clinical oncology. World J Stem Cells 2018; 10(12): 183-195
Url https://www.wjgnet.com/1948-0210/full/v10/i12/183.htm
DOI https://dx.doi.org/10.4252/wjsc.v10.i12.183
Full Article (PDF) WJSC-10-183.pdf
Full Article (Word) WJSC-10-183.docx
Manuscript File 42244-Review.docx
Answering Reviewers 42244-Answering reviewers.pdf
Audio Core Tip 42244-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 42244-Conflict-of-interest statement.pdf
Copyright License Agreement 42244-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 42244-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 42244-Language certificate.pdf
Peer-review Report 42244-Peer-review(s).pdf
Scientific Misconduct Check 42244-Scientific misconduct check.pdf
Scientific Editor Work List 42244-Scientific editor work list.pdf