Publication Name	World Journal of Cardiology
Manuscript ID	42949
Country	United States

Received	2018-10-24 06:25
Peer-Review Started	2018-10-24 07:53
To Make the First Decision	2018-12-11 01:18
Return for Revision	2018-12-17 03:12
Revised	2018-12-18 01:18
Second Decision	2019-01-08 12:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2019-01-09 04:16
Articles in Press	2019-01-09 04:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-02-22 05:53
Publish the Manuscript Online	2019-02-25 03:36

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Retrospective Study
Article Title	Prevalence and clinical characteristics associated with left atrial thrombus detection: Apixaban
Manuscript Source	Unsolicited Manuscript
All Author List	Hoyle L Whiteside, Arun Nagabandi, Kristen Brown, Deepak N Ayyala and Gyanendra K Sharma
Funding Agency and Grant Number
Corresponding Author	Hoyle L Whiteside, MD, Doctor, Division of Internal Medicine, Medical College of Georgia at Augusta University, 1120 15th St., Augusta, GA 30909, United States. hwhiteside@augusta.edu
Key Words	Atrial fibrillation; Anticoagulation; Left atrial appendage thrombus; Transesophageal echocardiography
Core Tip	The prevalence of left atrial appendage (LAA) thrombus detection by transesophageal echocardiogram (TEE) in patients with non-valvular atrial fibrillation (AF) anticoagulated with apixaban is not well defined and identification of additional risk factors may help guide the selection process for pre-procedural TEE. At our institution, the prevalence of thrombus detection in patients compliant with apixaban was 3.1%. Persistent AF, left ventricular ejection fraction < 30%, severe LA dilation, and reduced LAA velocity were associated with thrombus formation. Following multivariate logistic regression, persistent AF and reduced LAA velocity were identified as independent predictors of thrombus detection.
Publish Date	2019-02-25 03:36
Citation	Whiteside HL, Nagabandi A, Brown K, Ayyala DN, Sharma GK. Prevalence and clinical characteristics associated with left atrial thrombus detection: Apixaban. World J Cardiol 2019; 11(2): 84-93
URL	https://www.wjgnet.com/1949-8462/full/v11/i2/84.htm
DOI	https://dx.doi.org/10.4330/wjc.v11.i2.84

Full Article (PDF)	WJC-11-84.pdf
Full Article (Word)	WJC-11-84.docx
Manuscript File	42949-Review.docx
Answering Reviewers	42949-Answering reviewers.pdf
Audio Core Tip	42949-Audio core tip.mp3
Biostatistics Review Certificate	42949-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	42949-Conflict-of-interest statement.pdf
Copyright License Agreement	42949-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	42949-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	42949-Institutional review board statement.pdf
Supplementary Material	42949-Supplementary material.docx
Peer-review Report	42949-Peer-review(s).pdf
Scientific Misconduct Check	42949-Scientific misconduct check.pdf
Scientific Editor Work List	42949-Scientific editor work list.pdf