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3/26/2019 10:46:45 AM | Browse: 584 | Download: 755
Publication Name World Journal of Clinical Oncology
Manuscript ID 42964
Country/Territory United States
Received
2018-11-08 03:27
Peer-Review Started
2018-11-10 08:22
To Make the First Decision
2018-11-20 04:06
Return for Revision
2018-11-29 01:26
Revised
2018-12-27 21:35
Second Decision
2019-01-08 12:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-01-09 03:56
Articles in Press
2019-01-09 03:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-02-23 09:13
Publish the Manuscript Online
2019-03-22 11:26
ISSN 2218-4333 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Clinical Trials Study
Article Title Evaluation of a locked nucleic acid form of antisense oligo targeting HIF-1α in advanced hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Jennifer Wu, Merly Contratto, Krishna P Shanbhogue, Gulam A Manji, Bert H O'Neil, Anne Noonan, Robert Tudor and Ray Lee
Funding Agency and Grant Number
Corresponding Author Jennifer Wu, MD, Associate Professor, Attending Doctor, Division of Hematology and Oncology, Perlmutter Cancer Center, New York University School of Medicine, 462 First Ave, BCD556, New York, NY 10016, United States. jennifer.wu@nyumc.org
Key Words Hepatocellular carcinoma; Hypoxia-inducible factor 1α; RO7070179, Super-responder; Dynamic contrast-enhanced-magnetic resonance imaging
Core Tip Overexpression of hypoxia-inducible factor 1α (HIF-1α) correlates with poor prognosis in hepatocellular carcinoma (HCC) patients. HIF-1a inhibitor decreases HIF-1a mRNA and its downstream targets, it could be a potential treatment in HCC.
Publish Date 2019-03-22 11:26
Citation Wu J, Contratto M, Shanbhogue KP, Manji GA, O’Neil BH, Noonan A, Tudor R, Lee R. Evaluation of a locked nucleic acid form of antisense oligo targeting HIF-1α in advanced hepatocellular carcinoma. World J Clin Oncol 2019; 10(3): 149-160
URL https://www.wjgnet.com/2218-4333/full/v10/i3/149.htm
DOI https://dx.doi.org/10.5306/wjco.v10.i3.149
Full Article (PDF) WJCO-10-149.pdf
Full Article (Word) WJCO-10-149.docx
CONSORT 2010 Statement 42964-CONSORT 2010 Statement.pdf
Manuscript File 42964-Review.docx
Answering Reviewers 42964-Answering reviewers.pdf
Audio Core Tip 42964-Audio core tip.mp3
Clinical Trial Registration Statement 42964-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form 42964-Conflict-of-interest statement.pdf
Copyright License Agreement 42964-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 42964-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 42964-Institutional review board statement.pdf
Peer-review Report 42964-Peer-review(s).pdf
Scientific Misconduct Check 42964-Scientific misconduct check.pdf
Scientific Editor Work List 42964-Scientific editor work list.pdf