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1/30/2019 3:50:22 AM | Browse: 794 | Download: 1757
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Received |
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2018-10-30 10:26 |
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Peer-Review Started |
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2018-10-31 02:28 |
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First Decision by Editorial Office Director |
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2018-11-27 17:29 |
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Return for Revision |
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2018-12-03 06:54 |
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Revised |
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2018-12-08 15:04 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2018-12-12 08:52 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2018-12-12 19:43 |
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Articles in Press |
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2018-12-12 19:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-01-28 04:45 |
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Publish the Manuscript Online |
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2019-01-29 02:00 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Observational Study |
| Article Title |
Incidence, risk factors, and outcome of BK polyomavirus infection after kidney transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Evaldo Favi, Carmelo Puliatti, Rajesh Sivaprakasam, Mariano Ferraresso, Federico Ambrogi, Serena Delbue, Federico Gervasi, Ilaria Salzillo, Nicholas Raison and Roberto Cacciola |
| Funding Agency and Grant Number |
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| Corresponding Author |
Evaldo Favi, MD, PhD, Senior Lecturer, Surgeon, Renal Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza n.28, Milan 20122, Italy. evaldofavi@gmail.com |
| Key Words |
Polyomavirus; BK virus; Kidney transplantation; Outcome; Risk factors; Immunosuppression; Human leukocyte antigen; Rejection; Cytomegalovirus; Ethnicity |
| Core Tip |
Polyomavirus-associated nephropathy is a leading cause of kidney transplant failure. A systematic screening and treatment protocol in line with current international guideline was evaluated. Our results showed that despite early diagnosis and prompt intervention, graft-related outcomes for patients with BK-virus infection remain substantially inferior to control. We confirmed that initial viral load ≥ 10000 copies/mL is highly predictive of nephropathy. New putative risk factors for BK-viremia and nephropathy were also identified. Properly designed large multi-centre studies are warranted to further investigate individual susceptibility to BK-virus infection and validate alternative antiviral therapies. |
| Publish Date |
2019-01-29 02:00 |
| Citation |
Favi E, Puliatti C, Sivaprakasam R, Ferraresso M, Ambrogi F, Delbue S, Gervasi F, Salzillo I, Raison N, Cacciola R. Incidence, risk factors, and outcome of BK polyomavirus infection after kidney transplantation. World J Clin Cases 2019; 7(3): 270-290
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| URL |
https://www.wjgnet.com/2307-8960/full/v7/i3/270.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i3.270 |
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