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3/26/2019 10:47:13 AM | Browse: 264 | Download: 177
Publication Name World Journal of Stem Cells
Manuscript ID 43422
Country of Manuscript Source Italy
2018-11-10 08:46
Peer-Review Started
2018-11-11 12:11
To Make the First Decision
2018-11-29 07:59
Return for Revision
2018-12-05 08:00
2019-01-28 13:45
Second Decision
2019-03-07 09:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-12 22:49
Articles in Press
2019-03-12 22:49
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-03-26 04:06
Publish the Manuscript Online
2019-03-26 07:46
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Cell Biology
Manuscript Type Basic Study
Article Title Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells
Manuscript Source Invited Manuscript
All Author List Nicola Alessio, Tiziana Squillaro, Vincenzo Monda, Gianfranco Peluso, Marcellino Monda, Mariarosa AB Melone, Umberto Galderisi and Giovanni Di Bernardo
Funding Agency and Grant Number
Funding Agency Grant Number
2018 Grant of Experimental Medicine Department (Luigi Vanvitelli Campania University) to Umberto Galderisi and Marcellino Monda (partially)
Corresponding author Giovanni Di Bernardo, PhD, Associate Professor, Department of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania Luigi Vanvitelli, Via S.M. Costantinopoli 16, Naples 80138, Italy. gianni.dibernardo@unicampania.it
Keywords Mesenchymal stromal cells; Senescence; Cytokines; Adipogenesis; Brown fat
Core Tip Obesity may receive new hints from studies on skinny people (SP). These are individuals who show a poor or null gaining of body weight, in spite of high-calorie intake, by far exceeding the body requirements. We evaluated how circulating factors present in the SP sera may affect adipogenesis of mesenchymal stromal cells. Our finding suggests that sera from SP may promote brown adipogenesis rather that white adipocyte differentiation. Our data could explain why SP present normal body composition in spite of an excess of caloric intake.
Publish Date 2019-03-26 07:46
Citation Alessio N, Squillaro T, Monda V, Peluso G, Monda M, Melone MA, Galderisi U, Di Bernardo G. Circulating factors present in the sera of naturally skinny people may influence cell commitment and adipocyte differentiation of mesenchymal stromal cells. World J Stem Cells 2019; 11(3): 180-195
Url https://www.wjgnet.com/1948-0210/full/v11/i3/180.htm
DOI https://dx.doi.org/10.4252/wjsc.v11.i3.180
Full Article (PDF) WJSC-11-180.pdf
Full Article (Word) WJSC-11-180.docx
Manuscript File 43422-Review.docx
Answering Reviewers 43422-Answering reviewers.pdf
Audio Core Tip 43422-Audio core tip.mp3
Biostatistics Review Certificate 43422-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 43422-Conflict-of-interest statement.pdf
Copyright License Agreement 43422-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 43422-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 43422-Language certificate.pdf
Peer-review Report 43422-Peer-review(s).pdf
Scientific Misconduct Check 43422-Scientific misconduct check.pdf
Scientific Editor Work List 43422-Scientific editor work list.pdf