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1/30/2019 3:50:22 AM | Browse: 106 | Download: 75
Publication Name World Journal of Clinical Cases
Manuscript ID 44514
Country of Manuscript Source Finland
Received
2018-11-19 02:40
Peer-Review Started
2018-11-19 06:57
To Make the First Decision
2018-12-14 08:15
Return for Revision
2018-12-19 04:20
Revised
2018-12-21 09:33
Second Decision
2018-12-29 05:07
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-30 02:31
Articles in Press
2018-12-30 02:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-01-23 10:20
Publish the Manuscript Online
2019-01-29 02:00
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Retrospective Cohort Study
Article Title Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Henna K Söderström, Juha T Kauppi, Niku Oksala, Timo Paavonen, Leena Krogerus, Jari Räsänen and Tuomo Rantanen
Funding Agency and Grant Number
Correspondence To Tuomo Rantanen, MD, PhD, Professor, Department of Surgery, Kuopio University Hospital, Box 100, Kuopio 70029, Finland. tuomo.rantanen@kuh.fi
Keywords Esophageal adenocarcinoma; Heat shock proteins; Heat shock protein 27; Heat shock protein 70; Overexpression; Survival
Core Tip Heat shock proteins (HSPs) are classified according to molecular weight into distinct protein families, and they are present in all human cells. Overexpression of HSPs is associated with several malignancies and contributes to the development, progression, and metastasis of cancer, in addition to the inhibition of cellular death. In recent years, there has been active research into using HSP inhibitors in several malignancies. Because of the poor prognosis of esophageal adenocarcinoma (EAC), it would be valuable to find new biomarkers for the development of cancer treatments. We conducted the present study to analyze the expression of HSP27 and HSP70, and their association with survival, in patients with EAC.
Publish Date 2019-01-29 02:00
Citation Söderström HK, Kauppi JT, Oksala N, Paavonen T, Krogerus L, Räsänen J, Rantanen T. Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma. World J Clin Cases 2019; 7(3): 260-269
Url https://www.wjgnet.com/2307-8960/full/v7/i3/260.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i3.260
Full Article (PDF) WJCC-7-260.pdf
Full Article (Word) WJCC-7-260.docx
Manuscript File 44514-Review.docx
Answering Reviewers 44514-Answering reviewers.pdf
Audio Core Tip 44514-Audio core tip.wma
Biostatistics Review Certificate 44514-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 44514-Conflict-of-interest statement.pdf
Copyright License Agreement 44514-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 44514-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 44514-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 44514-Language certificate.pdf
Peer-review Report 44514-Peer-review(s).pdf
Scientific Misconduct Check 44514-Scientific misconduct check.pdf
Scientific Editor Work List 44514-Scientific editor work list.pdf