Publication Name	World Journal of Gastroenterology
Manuscript ID	44625
Country	China

Received	2018-11-21 02:10
Peer-Review Started	2018-11-22 02:14
To Make the First Decision	2018-12-12 07:57
Return for Revision	2018-12-17 07:01
Revised	2018-12-20 07:17
Second Decision	2018-12-27 11:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2018-12-28 05:04
Articles in Press	2018-12-28 05:04
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-01-04 01:10
Typeset the Manuscript	2019-01-17 07:13
Publish the Manuscript Online	2019-01-21 05:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Roles of Na+/Ca2+ exchanger 1 in digestive system physiology and pathophysiology
Manuscript Source	Unsolicited Manuscript
All Author List	Qiu-Shi Liao, Qian Du, Jun Lou, Jing-Yu Xu and Rui Xie
Funding Agency and Grant Number
Corresponding Author	Rui Xie, MD, PhD, Associate Professor, Department of Gastroenterology, Affiliated Hospital to Zunyi Medical College, No. 149 Dalian Road, Huichuan District, Zunyi 563000, Guizhou Province, China. 15120390646@163.com
Key Words	Na+/Ca2+ exchanger; Digestive system diseases; Ion channel; Sodium; Calcium
Core Tip	The Na+/Ca2+ exchange 1 protein (NCX1) is a membrane transporter and participates in the regulation of cellular Ca2+ homeostasis. As we known，NCX1 is expressed widely in various organs and tissues and plays an especially important role in the physiological and pathological processes of nerves and the cardiovascular system. This review aims to explore the roles of NCX1 in digestive system physiology and pathophysiology in order to guide clinical treatments.
Publish Date	2019-01-21 05:38
Citation	Liao Qs, Du Q, Lou J, Xu Jy, Xie R. Roles of Na+/Ca2+ exchanger 1 in digestive system physiology and pathophysiology. World J Gastroenterol 2019; 25(3): 287-299
URL	https://www.wjgnet.com/1007-9327/full/v25/i3/287.htm
DOI	https://dx.doi.org/10.3748/wjg.v25.i3.287

Full Article (PDF)	WJG-25-287.pdf
Full Article (Word)	WJG-25-287.docx
Manuscript File	44625-Review.docx
Answering Reviewers	44625-Answering reviewers.pdf
Audio Core Tip	44625-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	44625-Conflict-of-interest statement.pdf
Copyright License Agreement	44625-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	44625-Language certificate.pdf
Peer-review Report	44625-Peer-review(s).pdf
Scientific Misconduct Check	44625-Scientific misconduct check.pdf
Scientific Editor Work List	44625-Scientific editor work list.pdf