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5/20/2019 6:04:05 AM | Browse: 69 | Download: 31
Publication Name World Journal of Gastroenterology
Manuscript ID 45225
Country of Manuscript Source United States
Received
2019-02-02 05:45
Peer-Review Started
2019-02-06 05:20
To Make the First Decision
2019-02-14 01:10
Return for Revision
2019-02-15 04:43
Revised
2019-03-27 05:30
Second Decision
2019-03-29 10:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-03-30 00:39
Articles in Press
2019-03-30 00:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-05-14 00:32
Publish the Manuscript Online
2019-05-14 07:58
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Minireviews
Article Title Harnessing the potential of gene editing technology using CRISPR in inflammatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List Viktor Limanskiy, Arpita Vyas, Lakshmi Shankar Chaturvedi and Dinesh Vyas
Funding Agency and Grant Number
Correspondence To Dinesh Vyas, MD, MSc, Associate Professor, Director, Surgeon, Associate Dean of Surgery Research, Department of Surgery, San Joaquin General Hospital, 500 West Hospital Road, French Camp, CA95231, United States. dineshvyas@yahoo.com
Keywords Clustered regularly interspersed short palindromic repeats; Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Gene excision; Gene editing; Gene therapy; Financial impact of inflammatory bowel disease on healthcare; Clustered regularly interspersed short palindromic repeats crossfire
Core Tip Using clustered regularly interspaced short palindromic repeats/CRISPR associated protein 9 (CRISPR/Cas9) to harness the potential of gene editing technology implicated in inflammatory bowel disease. This revolutionary way of editing genes and its application of gene manipulation is only gaining momentum. Genes such as Gatm (Glycine amidinotransferase, mitochondrial) and nucleotide-binding oligomerization domain-containing protein 2 have been utilized to show CRISPR is able to manipulate these genes precisely, and this is just the beginning.
Publish Date 2019-05-14 07:58
Citation Limanskiy V, Vyas A, Chaturvedi LS, Vyas D. Harnessing the potential of gene editing technology using CRISPR in inflammatory bowel disease. World J Gastroenterol 2019; 25(18): 2177-2187
Url https://www.wjgnet.com/1007-9327/full/v25/i18/2177.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i18.2177
Full Article (PDF) WJG-25-2177.pdf
Full Article (Word) WJG-25-2177.docx
Manuscript File 45225-Review.docx
Answering Reviewers 45225-Answering reviewers.pdf
Audio Core Tip 45225-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 45225-Conflict-of-interest statement.pdf
Copyright License Agreement 45225-Copyright license agreement.pdf
Video 45225-Video.mp4
Peer-review Report 45225-Peer-review(s).pdf
Scientific Misconduct Check 45225-Scientific misconduct check.pdf
Scientific Editor Work List 45225-Scientific editor work list.pdf