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9/23/2019 3:28:17 AM | Browse: 65 | Download: 88
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 46230
Country of Manuscript Source Taiwan
Received
2019-03-15 03:09
Peer-Review Started
2019-03-18 00:19
To Make the First Decision
2019-06-05 06:34
Return for Revision
2019-06-06 03:45
Revised
2019-07-05 05:51
Second Decision
2019-08-16 08:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-08-19 03:14
Articles in Press
2019-08-19 03:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-09-08 03:49
Publish the Manuscript Online
2019-09-12 10:38
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019 Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Oncology
Manuscript type Review
Article Title Tumor progression-dependent angiogenesis in gastric cancer and its potential application
Manuscript Source Invited Manuscript
All Author List Ming-Ming Tsai and Hsi-Lung Hsieh
Funding Agency and Grant Number
Correspondence To Ming-Ming Tsai, PhD, Associate Professor, Department of Nursing, Division of Basic Medical Sciences,, Chang-Gung University of Science and Technology, 261 Wen-hwa 1 Road, Taoyuan 333, Taiwan. mmtsai@mail.cgust.edu.tw
Keywords Gastric cancer; Angiogenesis; Vascular endothelial cell; Angiogenic phenotype switch; Anti-angiogenesis; Tumor dormancy
Core Tip Tumor angiogenesis in GC and anti-angiogenic therapies for GC, including information from their preclinical to clinical trials and/or application, are discussed. The anti-angiogenic strategies include decreasing the expression of pro-angiogenic ligands and their receptors, increasing the level of angiogenic inhibitors, the direct targeting of the inner walls of ECs, and the administration of cell-cell adhesion inhibitors for advanced GC. This review provides a brief description of various tumor angiogenic factors for the purposes of diagnosis, prognosis and therapeutics and describes the anti-angiogenic drugs that are currently being investigated in preclinical and clinical trials. Hopefully, based on the molecular mechanism of tumor angiogenesis, we highlight the accuracy of diagnosis and prognosis and the selection of the most appropriate therapy for GC patients.
Publish Date 2019-09-12 10:38
Citation Hsieh HL, Tsai MM. Tumor progression-dependent angiogenesis in gastric cancer and its potential application. World J Gastrointest Oncol 2019; 11(9): 686-704
Url https://www.wjgnet.com/1948-5204/full/v11/i9/686.htm
DOI https://dx.doi.org/10.4251/wjgo.v11.i9.686
Full Article (PDF) WJGO-11-686.pdf
Full Article (Word) WJGO-11-686.docx
Manuscript File 46230-Review.docx
Answering Reviewers 46230-Answering reviewers.pdf
Audio Core Tip 46230-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 46230-Conflict-of-interest statement.pdf
Copyright License Agreement 46230-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 46230-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 46230-Language certificate.pdf
Peer-review Report 46230-Peer-review(s).pdf
Scientific Misconduct Check 46230-Scientific misconduct check.pdf
Scientific Editor Work List 46230-Scientific editor work list.pdf