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5/28/2019 12:12:53 AM | Browse: 627 | Download: 994
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Received |
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2019-02-13 04:31 |
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Peer-Review Started |
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To Make the First Decision |
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2019-03-08 04:00 |
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Return for Revision |
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2019-03-08 04:16 |
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Revised |
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2019-05-08 02:49 |
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Second Decision |
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2019-05-17 07:02 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-21 18:34 |
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Articles in Press |
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2019-05-21 18:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-05-23 19:28 |
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Typeset the Manuscript |
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2019-05-25 07:13 |
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Publish the Manuscript Online |
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2019-05-27 08:24 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Methodology |
| Manuscript Type |
Basic Study |
| Article Title |
Hepatitis C virus antigens enzyme immunoassay for one-step diagnosis of hepatitis C virus co-infection in human immunodeficiency virus infected individuals
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ke-Qin Hu, Wei Cui, Susan D Rouster and Kenneth E Sherman |
| Funding Agency and Grant Number |
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| Corresponding Author |
Ke-Qin Hu, MD, Professor, Div Gastroenterol and Hepatol, University of California, Irvine School of Medicine, Division of Gastroenterology and Hepatology and Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA 92868, USA. kqhu@uci.edu, Orange, CA 92617, United States. kqhu@uci.edu |
| Key Words |
Hepatitis C virus; Hepatitis C virus antigens; Hepatitis C virus core antigen; Hepatitis C virus diagnostic test; Diagnostic assay; Enzyme immunoassay |
| Core Tip |
We recently developed a novel and highly sensitive and specific hepatitis C virus antigens (HCV-Ags) enzyme immunoassay (EIA) for one-step diagnosis of viremic HCV infection. The present blindly tested this test’s performance in 147 sera, 10 without HCV or HIV infection; 54, viremic HCV monoinfection; 38, viremic HCV/HIV coinfection; and 45, viremic HCV and non-viremic HIV coinfection. Our results demonstrated that the HCV-Ags EIA is highly sensitive and specific in the setting of HIV coinfection, regardless of HIV infection status and CD4 count. These data support the clinical application of our HCV-Ags test in one-step diagnosis of HCV infection in HIV-infected individuals. |
| Publish Date |
2019-05-27 08:24 |
| Citation |
Hu KQ, Cui W, Rouster SD, Sherman KE. Hepatitis C virus antigens enzyme immunoassay for one-step diagnosis of hepatitis C virus co-infection in human immunodeficiency virus infected individuals. World J Hepatol 2019; 11(5): 442-449 |
| URL |
https://www.wjgnet.com/1948-5182/full/v11/i5/442.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v11.i5.442 |
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