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5/28/2019 12:12:53 AM | Browse: 71 | Download: 46
Publication Name World Journal of Hepatology
Manuscript ID 46458
Country of Manuscript Source United States
Received
2019-02-13 04:31
Peer-Review Started
To Make the First Decision
2019-03-08 04:00
Return for Revision
2019-03-08 04:16
Revised
2019-05-08 02:49
Second Decision
2019-05-17 07:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-21 18:34
Articles in Press
2019-05-21 18:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-05-23 19:28
Typeset the Manuscript
2019-05-25 07:13
Publish the Manuscript Online
2019-05-27 08:24
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Methodology
Manuscript type Basic Study
Article Title Hepatitis C virus antigens enzyme immunoassay for one-step diagnosis of hepatitis C virus co-infection in human immunodeficiency virus infected individuals
Manuscript Source Unsolicited Manuscript
All Author List Ke-Qin Hu, Wei Cui, Susan D Rouster and Kenneth E Sherman
Funding Agency and Grant Number
Correspondence To Ke-Qin Hu, MD, Professor, Div Gastroenterol and Hepatol, University of California, Irvine School of Medicine, Division of Gastroenterology and Hepatology and Chao Family Comprehensive Cancer Center, University of California Irvine Medical Center, Orange, CA 92868, USA. kqhu@uci.edu, Orange, CA92617, United States. kqhu@uci.edu
Keywords Hepatitis C virus; Hepatitis C virus antigens; Hepatitis C virus core antigen; Hepatitis C virus diagnostic test; Diagnostic assay; Enzyme immunoassay
Core Tip We recently developed a novel and highly sensitive and specific hepatitis C virus antigens (HCV-Ags) enzyme immunoassay (EIA) for one-step diagnosis of viremic HCV infection. The present blindly tested this test’s performance in 147 sera, 10 without HCV or HIV infection; 54, viremic HCV monoinfection; 38, viremic HCV/HIV coinfection; and 45, viremic HCV and non-viremic HIV coinfection. Our results demonstrated that the HCV-Ags EIA is highly sensitive and specific in the setting of HIV coinfection, regardless of HIV infection status and CD4 count. These data support the clinical application of our HCV-Ags test in one-step diagnosis of HCV infection in HIV-infected individuals.
Publish Date 2019-05-27 08:24
Citation Hu KQ, Cui W, Rouster SD, Sherman KE. Hepatitis C virus antigens enzyme immunoassay for one-step diagnosis of hepatitis C virus co-infection in human immunodeficiency virus infected individuals. World J Hepatol 2019; 11(5): 442-449
Url https://www.wjgnet.com/1948-5182/full/v11/i5/442.htm
DOI https://dx.doi.org/10.4254/wjh.v11.i5.442
Full Article (PDF) WJH-11-442.pdf
Full Article (Word) WJH-11-442.docx
Manuscript File FP6861_de16_CE1RUSHMS_edit.docx
Answering Reviewers 46458-Answering reviewers.pdf
Audio Core Tip 46458-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 46458-Conflict-of-interest statement.pdf
Copyright License Agreement 46458-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 46458-Institutional review board statement.pdf
Peer-review Report 46458-Peer-review(s).pdf
Scientific Misconduct Check 46458-Scientific misconduct check.pdf
Scientific Editor Work List 46458-Scientific editor work list.pdf