Publication Name	World Journal of Stem Cells
Manuscript ID	46953
Country	Spain

Received	2019-02-28 02:02
Peer-Review Started	2019-03-04 10:47
To Make the First Decision	2019-06-05 06:26
Return for Revision	2019-06-27 01:06
Revised	2019-07-31 11:14
Second Decision	2019-08-07 00:46
Accepted by Journal Editor-in-Chief	2019-08-07 23:55
Accepted by Company Editor-in-Chief	2019-08-27 23:22
Articles in Press	2019-08-27 23:22
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-09-03 19:05
Typeset the Manuscript	2019-09-17 10:23
Publish the Manuscript Online	2019-09-25 03:03

ISSN	1948-0210 (online)
Open Access	This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Cell Biology
Manuscript Type	Review
Article Title	Suitability and limitations of mesenchymal stem cells to elucidate human bone illness
Manuscript Source	Invited Manuscript
All Author List	Izaskun Mitxitorena, Arantza Infante, Blanca Gener and Clara I Rodríguez
Funding Agency and Grant Number	Funding Agency Grant Number ISCIII PI15/00820 ISCIII PI18/00202 Basque Country government kk-2018/00031/BC Fundación Mutua Madrileña AP165892017
Corresponding Author	Clara I Rodríguez, PhD, Senior Scientist, Stem Cells and Cell Therapy Laboratory, BioCruces Bizkaia Health Research Institute, Cruces University Hospital, Plaza de Cruces S/N, Barakaldo 48903, Bizkaia, Spain. cirodriguez@osakidetza.eus
Key Words	Mesenchymal stem cells; Bone illness; Osteoporosis; Osteogenesis; Osteoanabolic therapies; In vitro cell models
Core Tip	Human mesenchymal stem cells (hMSCs) have emerged as a encouraging therapeutic strategy for the treatment of bone diseases. Moreover, certain limitations of animal models for the study of bone disorders highlight the suitability and benefits of hMSCs for the elucidation of these pathologies. The current review explains the available strategies based on hMSCs for bone illness new treatments development and future directions in the field for a more accurate knowledge of the cause underlying these human pathologies.
Publish Date	2019-09-25 03:03
Citation	Mitxitorena I, Infante A, Gener B, Rodríguez CI. Suitability and limitations of mesenchymal stem cells to elucidate human bone illness. World J Stem Cells 2019; 11(9):578-593
URL	https://www.wjgnet.com/1948-0210/full/v11/i9/578.htm
DOI	https://dx.doi.org/10.4252/wjsc.v11.i9.578

Full Article (PDF)	WJSC-11-578.pdf
Full Article (Word)	WJSC-11-578.docx
Manuscript File	FP6984_ce16_CE1MS_confirm.docx
Answering Reviewers	46953-Answering reviewers.pdf
Audio Core Tip	46953-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	46953-Conflict-of-interest statement.pdf
Copyright License Agreement	46953-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	46953-Grant application form(s).pdf
Peer-review Report	46953-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	46953-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	46953-Scientific misconduct check.pdf
Scientific Editor Work List	46953-Scientific editor work list.pdf