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7/23/2019 6:56:02 AM | Browse: 54 | Download: 34
Publication Name World Journal of Gastroenterology
Manuscript ID 47403
Country of Manuscript Source United States
Received
2019-03-15 03:06
Peer-Review Started
2019-03-15 06:18
To Make the First Decision
2019-04-11 08:25
Return for Revision
2019-04-12 00:46
Revised
2019-04-25 16:55
Second Decision
2019-05-17 09:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-18 12:45
Articles in Press
2019-05-18 12:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-07-04 07:11
Publish the Manuscript Online
2019-07-06 06:23
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Review
Article Title Revisiting the liver’s role in transplant alloimmunity
Manuscript Source Invited Manuscript
All Author List Nitin Abrol, Caroline C Jadlowiec and Timucin Taner
Funding Agency and Grant Number
Correspondence To Timucin Taner, FACS, MD, PhD, Associate Professor, Surgeon, William J. von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, 200 First Street Southwest, Rochester, MN55905, United States. taner.timucin@mayo.edu
Keywords Liver transplantation; Alloimmunity; Liver-kidney transplant; Tolerance; Rejection
Core Tip The liver not only protects itself from host alloimmune responses, but also modulates alloimmune responses to other simultaneously transplanted solid organs like heart or kidney. The titer of donor specific alloantibodies decreases after liver transplantation, making transplantation of other solid organs possible even in highly sensitized high-risk patients. The immune cells from the liver allograft cross-talk with recipient immune cells and modulate the immune system towards tolerance. The cross-talk between these cells suppress the genes involved in alloimmunity and upregulate the genes involved in tissue repair and metabolism.
Publish Date 2019-07-06 06:23
Citation Abrol N, Jadlowiec CC, Taner T. Revisiting liver’s role in transplant alloimmunity. World J Gastroenterol 2019; 25(25): 3123-3135
Url https://www.wjgnet.com/1007-9327/full/v25/i25/3123.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i25.3123
Full Article (PDF) WJG-25-3123.pdf
Full Article (Word) WJG-25-3123.docx
Manuscript File 47403-Review.docx
Answering Reviewers 47403-Answering reviewers.pdf
Audio Core Tip 47403-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 47403-Conflict-of-interest statement.pdf
Copyright License Agreement 47403-Copyright license agreement.pdf
Peer-review Report 47403-Peer-review(s).pdf
Scientific Misconduct Check 47403-Scientific misconduct check.pdf
Scientific Editor Work List 47403-Scientific editor work list.pdf