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8/8/2019 2:01:02 AM | Browse: 27 | Download: 12
Publication Name World Journal of Gastroenterology
Manuscript ID 47519
Country of Manuscript Source United States
Received
2019-03-19 01:13
Peer-Review Started
2019-03-19 03:47
To Make the First Decision
2019-04-30 10:23
Return for Revision
2019-05-05 01:27
Revised
2019-06-13 02:40
Second Decision
2019-06-17 10:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-06-23 01:57
Articles in Press
2019-06-23 01:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-07-26 06:54
Publish the Manuscript Online
2019-07-28 10:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Review
Article Title Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma
Manuscript Source Invited Manuscript
All Author List Clifford Akateh, Sylvester M Black, Lanla F Conteh, Eric D. Miller, Anne Noonan, Eric D Elliott, Timothy M Pawlik, Allan Tsung and Jordan M Cloyd
Funding Agency and Grant Number
Correspondence To Jordan M Cloyd, MD, Assistant Professor, Department of Surgery, The Ohio State University, 410 W 10th Ave, N-907, Columbus, OH43210, United States. jordan.cloyd@osumc.edu
Keywords Hepatocellular carcinoma; Neoadjuvant therapy; Adjuvant therapy; Neoplasm recurrence; Hepatectomy; Liver cirrhosis
Core Tip Liver resection is an important curative-intent treatment option for patients with hepatocellular carcinoma (HCC). However, advanced disease, underlying chronic liver disease and/or cirrhosis, limits the proportion of patients who are surgical candidates. Recurrent disease is unfortunately common even after undergoing resection. As such, the benefits of neoadjuvant and adjuvant treatment strategies aimed at improving resectability and decreasing recurrence rates are of great interest. While high-level evidence to guide treatment decision making is lacking, recent advances in locoregional and systemic therapies, including antiviral treatment and immunotherapy, raise the prospect of novel approaches that may improve the outcomes of patients with HCC.
Publish Date 2019-07-28 10:51
Citation Akateh C, Black SM, Conteh L, Miller ED, Noonan A, Elliott E, Pawlik TM, Tsung A, Cloyd JM. Neoadjuvant and adjuvant treatment strategies for hepatocellular carcinoma. World J Gastroenterol 2019; 25(28): 3704-3721
Url https://www.wjgnet.com/1007-9327/full/v25/i28/3704.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i28.3704
Full Article (PDF) WJG-25-3704.pdf
Full Article (Word) WJG-25-3704.docx
Manuscript File 47519-Review.docx
Answering Reviewers 47519-Answering reviewers.pdf
Audio Core Tip 47519-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 47519-Conflict-of-interest statement.pdf
Copyright License Agreement 47519-Copyright license agreement.pdf
Peer-review Report 47519-Peer-review(s).pdf
Scientific Misconduct Check 47519-Google-MA RY-1.png
Scientific Misconduct Check 47519-Google-MA RY-2.png
Scientific Misconduct Check 47519-Scientific misconduct check.pdf
Scientific Editor Work List 47519-Scientific editor work list.pdf