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5/17/2019 6:59:17 AM | Browse: 566 | Download: 751
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Received |
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2019-03-18 04:13 |
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Peer-Review Started |
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2019-03-19 08:59 |
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To Make the First Decision |
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2019-04-19 00:52 |
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Return for Revision |
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2019-04-19 07:13 |
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Revised |
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2019-04-22 14:15 |
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Second Decision |
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2019-04-23 04:31 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-04-23 05:40 |
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Articles in Press |
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2019-04-23 05:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-04-25 22:03 |
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Typeset the Manuscript |
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2019-04-29 06:57 |
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Publish the Manuscript Online |
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2019-04-30 03:02 |
| ISSN |
2308-3840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Review |
| Article Title |
Subcellular expression of maspin – from normal tissue to tumor cells
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Laura Banias, Ioan Jung and Simona Gurzu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Romanian National Authority for Scientific Research, CNCS – UEFISCDI |
20 PCCF/2018, code: PN-III-P4-ID-PCCF-2016-0006 |
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| Corresponding Author |
Simona Gurzu, MD, PhD, Chief Doctor, Director, Director, Doctor, Doctor, Full Professor, Research Fellow, Research Scientist, Department of Pathology, University of Medicine, Pharmacy, Sciences and Technology of Tirgu-Mures, 38 Gheorghe Marinescu Street, Targu Mures 540139, Romania. simonagurzu@yahoo.com |
| Key Words |
Maspin; SerpinB5; Prognosis; Cancer; Tumor suppressor |
| Core Tip |
The present paper is concentrated on showing different patterns of immunohistochemical expression and mRNA levels of maspin, as presented in published studies from 1994 until the beginning of 2019, which were included in the PubMed database. It was proved that Maspin, a member of the serine protease inhibitor family, functions as a tumor suppressor or tumor promoter. Its function is organ-related and depends on its subcellular localization. In colorectal cancer specimens, Maspin was proved a helpful marker of budding assessment. In most of the malignant tumors, it was demonstrated to be an independent prognostic and predictive factor. |
| Publish Date |
2019-04-30 03:02 |
| Citation |
Banias L, Jung I, Gurzu S. Subcellular expression of maspin – from normal tissue to tumor cells. World J Meta-Anal 2019; 7(4): 142-155 |
| URL |
https://www.wjgnet.com/2308-3840/full/v7/i4/142.htm |
| DOI |
https://dx.doi.org/10.13105/wjma.v7.i4.142 |
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