Publication Name	World Journal of Clinical Cases
Manuscript ID	49190
Country	China

Received	2019-05-18 05:32
Peer-Review Started	2019-05-18 06:19
To Make the First Decision	2019-06-11 07:55
Return for Revision	2019-06-11 08:58
Revised	2019-06-21 16:21
Second Decision	2019-07-12 09:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-07-20 04:10
Articles in Press	2019-07-20 04:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2019-08-09 18:16
Typeset the Manuscript	2019-08-23 06:57
Publish the Manuscript Online	2019-08-26 02:56

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Application of Newcastle disease virus in the treatment of colorectal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Hui Song, Li-Ping Zhong, Jian He, Yong Huang and Yong-Xiang Zhao
Funding Agency and Grant Number
Corresponding Author	Yong-Xiang Zhao, MD, PhD, Professor, National Center for International Research of Bio-targeting Theranostics, Guangxi Key Laboratory of Bio-targeting Theranostics, Collaborative Innovation Center for Targeting Tumor Diagnosis and Therapy, Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China. yongxiang_zhao@126.com
Key Words	Newcastle disease virus; Exogenous gene; Armed virus; Oncolytic therapy; Colorectal cancer;
Core Tip	At present, the main treatment for colorectal cancer (CRC) are surgical treatment and chemotherapy, but the majority of patients die due to liver or lung metastasis or recurrence. Therefore, there is an urgent need to find more effective treatment strategies to reduce their mortality. Newcastle disease virus (NDV) can selectively infect tumor cells, and can also improve the ability of NDV to resist CRC by constructing an autologous tumor vaccine (ATV-NDV). The series clinical treatment tests have also proved its good therapeutic effect, and it is hopeful to become a new treatment for CRC.
Publish Date	2019-08-26 02:56
Citation	Song H, Zhong LP, He J, Huang Y, Zhao YX. Application of Newcastle disease virus in the treatment of colorectal cancer. World J Clin Cases 2019; 2143-2154
URL	https://www.wjgnet.com/2307-8960/full/v7/i16/2143.htm
DOI	https://dx.doi.org/10.12998/wjcc.v7.i16.2143

Full Article (PDF)	WJCC-7-2143.pdf
Full Article (Word)	WJCC-7-2143.docx
Manuscript File	FP6931_de16_CE1MS_edit2.docx
Answering Reviewers	49190-Answering reviewers.pdf
Audio Core Tip	49190-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	49190-Conflict-of-interest statement.pdf
Copyright License Agreement	49190-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	49190-Language certificate.pdf
Peer-review Report	49190-Peer-review(s).pdf
Scientific Misconduct Check	49190-Scientific misconduct check.pdf
Scientific Editor Work List	49190-Scientific editor work list.pdf
CrossCheck Report	49190-CrossCheck Report.pdf