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11/15/2019 9:25:09 AM | Browse: 51 | Download: 65
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 49764
Country of Manuscript Source Italy
Received
2019-06-15 09:37
Peer-Review Started
2019-06-19 09:31
To Make the First Decision
2019-08-01 00:23
Return for Revision
2019-08-01 08:38
Revised
2019-08-01 14:33
Second Decision
2019-08-16 09:37
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-08-21 01:25
Articles in Press
2019-08-21 01:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-09-19 03:43
Typeset the Manuscript
2019-10-24 12:21
Publish the Manuscript Online
2019-11-15 07:45
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript Type Editorial
Article Title New era for pancreatic endoscopic ultrasound: From imaging to molecular pathology of pancreatic cancer
Manuscript Source Invited Manuscript
All Author List Livia Archibugi, Sabrina Gloria Giulia Testoni, Miriam Redegalli, Maria Chiara Petrone, Michele Reni, Massimo Falconi, Claudio Doglioni, Gabriele Capurso and Paolo Giorgio Arcidiacono
Funding Agency and Grant Number
Funding Agency Grant Number
Associazione Italiana Ricerca sul Cancro (AIRC) IG 17177
Corresponding author Gabriele Capurso, MD, PhD, Chief Doctor, Chief of Clinical Research, Pancreato-Biliary Endoscopy and EUS Division, Pancreas Translational and Clinical Research Center, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, Milano 20132, Italy. capurso.gabriele@hsr.it
Keywords Endoscopic ultrasound; Pancreatic cancer; Ribonucleic acid; Deoxyribonucleic acid; Mutation; Molecular
Core Tip Surgical formalin-fixed-paraffin-embedded samples are not representative of all pancreatic ductal adenocarcinoma (PDAC) patients and it was proved how “pre-resection” fine-needle aspiration smears are a better deoxyribonucleic acid (DNA) source. endoscopic ultrasound (EUS) is therefore the recommended method to obtain tumour’s molecular signature analysis. However, important limitations of EUS-acquired samples are: intratumoral heterogeneity, tumoral cells total amount and lesional-to-non-lesional cell ratio. Furthermore, sample handling and stock change DNA and even more ribonucleic acid extraction efficiency, a current “hot topic” as also patient-derived xenografts or organoids generation. Optimization and standardization of procedures from EUS-guided biopsy to samples handling and molecular analyses are, therefore, essential to allow a “precision medicine” for PDAC.
Publish Date 2019-11-15 07:45
Citation Archibugi L, Testoni SGG, Redegalli M, Petrone MC, Reni M, Falconi M, Doglioni C, Capurso G, Arcidiacono PG. New era for pancreatic endoscopic ultrasound: From imaging to molecular pathology of pancreatic cancer. World J Gastrointest Oncol 2019; 11(11): 933-945
Url https://www.wjgnet.com/1948-5204/full/v11/i11/933.htm
DOI https://dx.doi.org/10.4251/wjgo.v11.i11.933
Full Article (PDF) WJGO-11-933.pdf
Full Article (Word) WJGO-11-933.docx
Manuscript File 49764-Review_Edited.docx
Answering Reviewers 49764-Answering reviewers.pdf
Audio Core Tip 49764-Audio core tip.mp4
Conflict-of-Interest Disclosure Form 49764-Conflict-of-interest statement.pdf
Copyright License Agreement 49764-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 49764-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 49764-Language certificate.pdf
Peer-review Report 49764-Peer-review(s).pdf
Scientific Misconduct Check 49764-Scientific misconduct check.pdf
Scientific Editor Work List 49764-Scientific editor work list.pdf